Evidence map›Paper›PMID 32675924›Full record

ArticleActa Cardiologica Sinica2020

Application and Comparison of Different Prognostic Scoring Systems in Patients Who Underwent Cardiologist-Managed Percutaneous Cardiopulmonary Support.

Shih-Chieh Chien, Wei-Ren Lan, Shu-Hao Wu, Chen-Yen Chien, Yu-Shan Chien, Chi-In Lo, Cheng-Ting Tsai, Chun-Yen Chen

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Article in Acta Cardiologica Sinica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Shih-Chieh ChienDepartment of Critical Care Medicine.
Wei-Ren LanCardiovascular Division, Department of Internal Medicine.
Shu-Hao WuCardiovascular Division, Department of Internal Medicine.
Chen-Yen ChienDivision of Cardiovascular Surgery, Department of Surgery, MacKay Memorial Hospital, Taipei.
Yu-Shan ChienDepartment of Critical Care Medicine.
Chi-In LoDepartment of Critical Care Medicine.
Cheng-Ting TsaiCardiovascular Division, Department of Internal Medicine.
Chun-Yen ChenCardiovascular Division, Department of Internal Medicine, MacKay Memorial Hospital, MacKay Medical College, New Taipei City, Taiwan.

Funding

Specificity and Validity of Oxidative Stress Model of Chronic Fatigue SyndromeR01MH100005 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI SHUNGU, DIKOMA C · 2013 to 2016
$2.0M
NIMH NIH HHS R01 MH100005
6 · The paper itself

Abstract

backgroundTemporary mechanical support, including percutaneous cardiopulmonary support (PCPS), is crucial for reversing patients' compromised hemodynamic function. Knowledge about whether cardiologists can directly manage patients receiving PCPS and about the predictive values of different prognostic scores is insufficient.

methodsWe examined the data and in-hospital mortality of 45 eligible patients receiving cardiologist-managed PCPS from July 2012 to January 2019 in our institute. We compared different prognostic scores [namely Survival After Veno-arterial ECMO (SAVE), modified SAVE, prEdictioN of Cardiogenic shock OUtcome foR acute myocardial infarction patients salvaGed by VA-ECMO (ENCOURAGE), and Sequential Organ Failure Assessment (SOFA) scores] through area under the receiver operating characteristic curve (AUC) analysis.

resultsThe patients' mean age was 64.3 ± 11.3 years, and 71.1% were men. The overall in-hospital survival rate was 35.6%. Compared to survivors, nonsurvivors were more likely to have an ischemic etiology, cardiopulmonary resuscitation, and higher lactate levels. Survivors had higher SAVE (-5.9 vs. -11.4) and modified SAVE (4.2 vs. -7.1) scores than nonsurvivors (both p = 0.001), but SOFA (9.7 vs. 10.3) and ENCOURAGE (24.8 vs. 26.8) scores were similar (both p > 0.1). In multivariate models, only modified SAVE score remained statistically significant (hazard ratio: 0.96, 95% confidence interval: 0.93-1.00; p = 0.047). Modified SAVE score showed the best risk discrimination (AUC = 0.78).

conclusionsEstablishing regular and continual training protocols can enable cardiologists to perform emergency PCPS (without on-site surgery) and daily care for patients with refractory cardiogenic shock. The modified SAVE score facilitates risk stratification and future decision-making processes.

Indexed as

Cardiogenic shockPCPSPeripheral V-A ECMOPrognostic score

Identifiers

PMID32675924
PMCPMC7355122

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.