ArticleJournal of orthopaedics
Orthopedic manifestation as the presenting symptom of acute lymphoblastic leukemia.
Article in Journal of orthopaedics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Low Bone Turnover and Decreased Bone Matrix Mineralization at Diagnosis in Children with Acute Lymphoblastic Leukemia.Calcified tissue international · 2026Article
- Orthopedic manifestations as presenting symptoms in children with neuroblastoma: a retrospective case series and clinical review.Journal of orthopaedic surgery and research · 2026Review
- Leukemic Arthritis Mimicking Septic Arthritis in a Pediatric Patient.Journal of the Pediatric Orthopaedic Society of North America · 2025Article
- Identifying the characteristics of and developing a predictive model for differentiating cancer-related musculoskeletal symptoms from juvenile idiopathic arthritis.Pediatric rheumatology online journal · 2025Article
- Musculoskeletal involvement in childhood leukemia: Characteristics and survival outcomes.Pediatric rheumatology online journal · 2022Article
- Article
- Extramedullary manifestations in acute lymphoblastic leukemia in children: a systematic review and guideline-based approach of treatment.American journal of blood research · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe diagnosis of Acute lymphoblastic leukemia (ALL) is delayed due to vague presentation and normal hematological investigations.
objectiveThe objectives were to identify the frequency of ALL cases presented to the orthopedic department and with normal hematological investigations. MATERIAL AND
methods250 consecutive ALL cases were retrospectively evaluated to identify cases with musculoskeletal manifestations, and laboratory investigations.
resultsTwenty-two patients (4- vertebral compression fractures, 12- joint pain, 6- bone pain), presented primarily to the orthopedic department. Six patients had a normal peripheral smear.
conclusionThe primary physician should maintain a high index of suspicion despite a normal peripheral smear.
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