Evidence map›Paper›PMID 32675661›Full record

ArticleThe Journal of bone and joint surgery. American volume2020

Musculoskeletal Consequences of COVID-19.

Nathaniel P Disser, Andrea J De Micheli, Martin M Schonk, Maxwell A Konnaris, Alexander N Piacentini, Daniel L Edon, Brett G Toresdahl, Scott A Rodeo, Ellen K Casey, Christopher L Mendias

4 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in The Journal of bone and joint surgery. American volume, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 225 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
225citing papers in PubMed, 7 pooled it
31.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04734561 nacompletednot on this mapstarted 2021, after this paper: background citation

Effects of Respiratory Muscle Training on Quality of Life, Physical and Pulmonary Function and Psychological Status in Patients Who Have Had COVID-19 Disease

TypeinterventionalSponsorUniversidad Complutense de MadridRan2021 to 2021Enrolled88ConditionsCovid19, Respiratory Muscle Training, Respiratory Function Test, Quality of LifeArmsInspiratory muscle training group, Inspiratory muscle training placebo group, Inspiratory + expiratory muscle training group, Inspiratory + expiratory muscle training placebo group
NCT04784546 completednot on this mapstarted 2021, after this paper: background citation

Evaluation of Muscle Strength, Functional Independence, Myalgia Severity, Physical Fatigue and Dyspnea in Patients With COVID-19 Infection

TypeobservationalSponsorGazi UniversityRan2021 to 2021Enrolled76ConditionsCovid19
NCT04942249 unknown statusnot on this mapstarted 2021, after this paper: background citation

Long COVID in Military Organisations

TypeobservationalSponsorUniversity of ZurichRan2021 to 2021Enrolled500ConditionsCovid19ArmsNo intervention
NCT05813613 completednot on this mapstarted 2023, after this paper: background citation

Role of Artificial Intelligence in Predicting Muscle Fatigue Using Virtual Reality Training In Healthy And Post COVID19 Subjects

TypeobservationalSponsorBeirut Arab UniversityRan2023 to 2023Enrolled90ConditionsFatigueArmsSquatting with the aid of Kynapsis Virtual Training apparatus.
3 · Its place in the literature

Who cites it

225 citing papers in PubMed, 7 syntheses or guidelines pooled it, 466 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Article
  11. Article
  12. Article
  13. Myopathies in clinical care: a focus on treatable causes.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Musculoskeletal Symptoms and Post-COVID Functional Status among COVID-19 Survivors: A Single-Center Prospective Observational Study.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2025
    Article
  19. Review
  20. Review

165 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nathaniel P DisserHospital for Special Surgery, New York, NY.ORCID 0000-0002-4743-7475
Andrea J De MicheliHospital for Special Surgery, New York, NY.ORCID 0000-0002-9985-2638
Martin M SchonkHospital for Special Surgery, New York, NY.ORCID 0000-0002-0035-8219
Maxwell A KonnarisHospital for Special Surgery, New York, NY.ORCID 0000-0003-4893-1413
Alexander N PiacentiniHospital for Special Surgery, New York, NY.ORCID 0000-0002-9048-3549
Daniel L EdonHospital for Special Surgery, New York, NY.ORCID 0000-0001-9153-8153
Brett G ToresdahlHospital for Special Surgery, New York, NY.ORCID 0000-0003-3857-2779
Scott A RodeoHospital for Special Surgery, New York, NY.ORCID 0000-0002-0745-9880
Ellen K CaseyHospital for Special Surgery, New York, NY.ORCID 0000-0003-0139-8826
Christopher L MendiasHospital for Special Surgery, New York, NY.ORCID 0000-0002-2384-0171
Hospital for Special Surgery · US

Funding

Sex Differences in Tendon Growth and RemodelingR01AR063649 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RODEO, SCOTT A · 2013 to 2022
$3.6M
NIAMS NIH HHS R01 AR063649
6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is an emerging pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although the majority of patients who become infected with SARS-CoV-2 are asymptomatic or have mild symptoms, some patients develop severe symptoms that can permanently detract from their quality of life. SARS-CoV-2 is closely related to SARS-CoV-1, which causes severe acute respiratory syndrome (SARS). Both viruses infect the respiratory system, and there are direct and indirect effects of this infection on multiple organ systems, including the musculoskeletal system. Epidemiological data from the SARS pandemic of 2002 to 2004 identified myalgias, muscle dysfunction, osteoporosis, and osteonecrosis as common sequelae in patients with moderate and severe forms of this disease. Early studies have indicated that there is also considerable musculoskeletal dysfunction in some patients with COVID-19, although long-term follow-up studies have not yet been conducted. The purpose of this article was to summarize the known musculoskeletal pathologies in patients with SARS or COVID-19 and to combine this with computational modeling and biochemical signaling studies to predict musculoskeletal cellular targets and long-term consequences of the SARS-CoV-2 infection.

Indexed as

Angiotensin-Converting Enzyme 2BetacoronavirusBone and BonesComputer SimulationCoronavirus InfectionsCOVID-19HumansJointsMuscle, SkeletalMuscle WeaknessMusculoskeletal SystemMyalgiaPandemicsPeptidyl-Dipeptidase APneumonia, ViralSARS-CoV-2ACE2 protein, humanAngiotensin-Converting Enzyme 2Peptidyl-Dipeptidase ASerine EndopeptidasesTMPRSS2 protein, human

Identifiers

PMID32675661
PMCPMC7508274
OpenAlexW3027634504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.