ArticleAnnals of surgery2020
Radiological Simultaneous Portohepatic Vein Embolization (RASPE) Before Major Hepatectomy: A Better Way to Optimize Liver Hypertrophy Compared to Portal Vein Embolization.
Article in Annals of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 4 of them syntheses that pooled it.
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Who cites it
52 citing papers in PubMed, 4 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Meta-analysis of liver venous deprivation vs portal vein embolization in treating liver cancer with an insufficient liver remnant.Journal of the Chinese Medical Association : JCMA · 2025Pooled it
- A systematic review and meta-analysis of liver venous deprivation versus portal vein embolization before hepatectomy: future liver volume, postoperative outcomes, and oncological safety.Frontiers in medicine · 2023Pooled it
- Pooled it
- Pooled it
- When is enough enough?-predicting adequacy of portal vein embolization for hypertrophy of the future liver remnant in the age of liver venous deprivation.Hepatobiliary surgery and nutrition · 2026Article
- Sequential hepatectomy for hepatocellular carcinoma with inadequate future-liver-remnant after portal vein ligation in combination with apatinib plus camrelizumab (PLACES): a single-arm prospective pilot study.Hepatobiliary surgery and nutrition · 2026Article
- Efficacy of Sequential Hepatic Vein Embolization Following Portal Vein Embolization in Promoting Regeneration of Liver Volume and Function Before Right-Sided Major Hepatectomy.Annals of gastroenterological surgery · 2026Article
- Enhancing future liver remnant hypertrophy: innovative preoperative strategies and emerging technologies.Translational gastroenterology and hepatology · 2026Review
- Should all patients be offered liver venous deprivation for insufficient future liver remnant hypertrophy prior to major hepatectomy?Hepatobiliary surgery and nutrition · 2025Article
- Combined Portal and Hepatic Vein Embolization Produces Greater Hypertrophy than Portal Vein Embolization Alone with Similar Post-Hepatectomy Outcomes and is not Impacted by Hepatic Artery Infusion Chemotherapy.Annals of surgical oncology · 2025Article
- Augmenting the Future Liver Remnant Prior to Major Hepatectomy: A Review of Options on the Menu.Annals of surgical oncology · 2025Review
- Propensity Score-Matched Analysis of Liver Venous Deprivation and Portal Vein Embolization Before Planned Hepatectomy in Patients with Extensive Colorectal Liver Metastases and High-Risk Factors for Inadequate Regeneration.Annals of surgical oncology · 2025Article
- Safety of laparoscopic compared to open right hepatectomy after portal vein occlusion: results from a multicenter study.Surgical endoscopy · 2025Article
- Liver venous deprivation (LVD) before extended hepatectomy: a French multicentric retrospective cohort.Hepatobiliary surgery and nutrition · 2024Article
- Initial experience with Double-vein Embolization in Hungary.European journal of radiology open · 2024Article
- Histological and radiological analysis of simultaneous dual hepatic vein embolization for right-sided major hepatectomy.Surgery today · 2024Article
- Comprehensive Review of Future Liver Remnant (FLR) Assessment and Hypertrophy Techniques Before Major Hepatectomy: How to Assess and Manage the FLR.Annals of surgical oncology · 2024Review
- Article
- Transfemoral hepatic vein catheterization reduces procedure time in double vein embolization.CVIR endovascular · 2024Article
- Simultaneous embolization of the right portal and hepatic veins before intrahepatic cholangiocarcinoma resection.Einstein (Sao Paulo, Brazil) · 2024Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this retrospective study was to compare portal vein embolization (PVE) and radiologica simultaneous portohepatic vein embolization (RASPE) for future liver remnant (FLR) growth in terms of feasibility, safety, and efficacy. SUMMARY OF BACKGROUND DATA: After portal vein embolization (PVE), 15% of patients remain ineligible for hepatic resection due to insufficient hypertrophy of the FLR. RASPE has been proposed to induce FLR growth. MATERIALS AND
methodsBetween 2016 and 2018, 73 patients were included in the study. RASPE was proposed for patients with a ratio of FLR to total liver volume (FLR/TLV) of <25% (RASPE group). This group was compared to patients who underwent PVE for a FLR/TLV <30% (PVE group). Patients in the 2 groups were matched for age, sex, type of tumor, and number of chemotherapy treatments. FLR was assessed by computed tomography before and 4 weeks after the procedure.
resultsThe technical success rate in both groups was 100%. Morbidity post-embolization, and the time between embolization and surgery were similar between the groups. In the PVE group, the FLR/TLV ratio before embolization was 31.03% (range: 18.33%-38.95%) versus 22.91% (range: 16.55-32.15) in the RASPE group (P < 0.0001). Four weeks after the procedure, the liver volume increased by 28.98% (range: 9.31%-61.23%) in the PVE group and by 61.18% (range: 23.18%-201.56%) in the RASPE group (P < 0.0001). Seven patients in the PVE group, but none in the RASPE group, had postoperative liver failure (P = 0.012).
conclusionsRASPE can be considered as "radiological associating liver partition and portal vein ligation for staged hepatectomy." RASPE induced safe and profound growth of the FLR and was more efficient than PVE. RASPE also allowed for extended hepatectomy with less risk of post-operative liver failure.
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