ArticleGenes & development2020
Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis.
Open access · diamondAbstract readComparative Study
In one paragraph
Article in Genes & development, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
What it found
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Who cites it
61 citing papers in PubMed, 88 citations in OpenAlex.
- Comprehensive analysis of TEAD inhibition in meningioma identifies MEK and mTOR inhibition as effective combination therapies against resistant lines.bioRxiv : the preprint server for biology · 2026Article
- Regulation of YAP activity by nuclear G-actin binding.Nucleic acids research · 2026Article
- YAP1::TFE3 mediates endothelial-to-mesenchymal plasticity in epithelioid hemangioendothelioma.Molecular oncology · 2026Article
- NUP205 Stabilized YAP1 Protein to Stimulate Growth of Hepatocellular Carcinoma Cells in vitro and in vivo.Journal of hepatocellular carcinoma · 2026Article
- YAP1::MAML2 fusion, a newly identified genetic anomaly in a posterior fossa infant tumor, associated with the methylation class "embryonal tumor with multilayered rosettes, non-C19MC-altered" in the Heidelberg central nervous system tumor classifier and "embryonal tumor with multilayered rosettes-DICER" in the NIH classifier.Acta neuropathologica communications · 2025Article
- Filament formation and NAD processing by noncanonical human FAM118 sirtuins.Nature structural & molecular biology · 2025Article
- Article
- C-terminal fusion partner activity contributes to the oncogenic functions of YAP1::TFE3.Scientific reports · 2025Article
- C-terminal fusion partner activity contributes to the oncogenic functions of YAP1::TFE3.bioRxiv : the preprint server for biology · 2025Article
- TEAD1::NCOA2 fusion driver in primary central nervous system malignancy: case report.Acta neuropathologica · 2025Article
- Emerging regulatory mechanisms and functions of biomolecular condensates: implications for therapeutic targets.Signal transduction and targeted therapy · 2025Review
- RNA polymerase II at histone genes predicts outcome in human cancer.Science (New York, N.Y.) · 2025Article
- Chromatin profiling for everyone: FFPE-CUTAC for the theory and practice of modern molecular biology.Frontiers in epigenetics and epigenomics · 2025Article
- RNA Polymerase II hypertranscription at histone genes in cancer FFPE samples.bioRxiv : the preprint server for biology · 2024Article
- Malignant meningioma of the falx cerebri in a child: case report and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Review
- ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.Cell reports · 2024Article
- Non-supratentorial YAP1- fused ependymomas: report of two cases.Acta neuropathologica communications · 2024Article
- Asiaticoside inhibits breast cancer progression and tumor angiogenesis via YAP1/VEGFA signal pathway.Heliyon · 2024Article
- The Impact of Molecular and Genetic Analysis on the Treatment of Patients with Atypical Meningiomas.Diagnostics (Basel, Switzerland) · 2024Review
- Small blue round cell tumor with focal epithelial differentiation harboring a novel YAP1::LEUTX fusion with poor prognosis.Virchows Archiv : an international journal of pathology · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 3 countries.
Frank SzulzewskyHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.ORCID 0000-0001-5710-9590
Sonali AroraHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.ORCID 0000-0002-6661-3024
Pia HoellerbauerHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.ORCID 0000-0003-3672-5575
Claire KingDepartment of Oncology, Cambridge Cancer Center, Cambridge CB2 0RE, England.
Erica NathanDepartment of Oncology, Cambridge Cancer Center, Cambridge CB2 0RE, England.
Marina ChanHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Patrick J CiminoHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Tatsuya OzawaDivision of Brain Tumor Translational Research, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045, Japan.
Daisuke KawauchiHopp Children's Cancer Center Heidelberg (KiTZ), 69120 Heidelberg, Germany.
Kristian W PajtlerHopp Children's Cancer Center Heidelberg (KiTZ), 69120 Heidelberg, Germany.
Richard J GilbertsonDepartment of Oncology, Cambridge Cancer Center, Cambridge CB2 0RE, England.
Patrick J PaddisonHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Valeri VasioukhinHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.ORCID 0000-0002-6730-0281
Taranjit S GujralHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Eric C HollandHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.ORCID 0000-0002-3792-7120
Fred Hutch Cancer Center · USCancer Research UK Cambridge Center · GBUniversity of Washington · USGerman Cancer Research Center · DENational Cancer Research Institute · GB
Funding
Project 3: Single Cell Measures of Intratumor Diversity for Optimal Breast Cancer TherapyU54CA193461 · NCI · DANA-FARBER CANCER INST · PI POLYAK, KORNELIA · 2015 to 2020
$11.2MInterdisciplinary Tranining in Cancer ResearchT32CA080416 · NCI · UNIVERSITY OF WASHINGTON · PI STODDARD, BARRY L. · 1998 to 2023
$9.7MMechanisms and models of C11or95 and C11or95-RELA fusions (RELAFus )U54CA243125 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HOLLAND, ERIC C. · 2019 to 2022
$6.2MThe Role of Signaling Pathways in Brain Tumors in MiceR01CA100688 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI HOLLAND, ERIC C. · 2003 to 2013
$3.8MMYC-dependent loss of splicing fidelity in Glioblastoma multiformeR01CA190957 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PADDISON, PATRICK · 2015 to 2019
$2.2MBasal Cell Polarity Proteins in Normal Tissue Homeostasis and CancerR01CA234050 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI VASIOUKHIN, VALERI · 2019 to 2023
$2.0MUsing genetically engineered mouse models of brain tumors to develop therapeutic nanoparticles & biomaterialsR01CA195718 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HOLLAND, ERIC C., HOUGHTON, A MCGARRY · 2016 to 2018
$1.9MRegulation of Hippo Signaling by Src-Family KinasesR01CA188452 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI VASIOUKHIN, VALERI · 2014 to 2018
$1.8MCancer Research UK 26398NCI NIH HHS R01 CA100688NCI NIH HHS R01 CA188452NCI NIH HHS R01 CA190957NCI NIH HHS R01 CA195718NCI NIH HHS R01 CA234050NCI NIH HHS T32 CA080416NCI NIH HHS U54 CA193461NCI NIH HHS U54 CA243125
Abstract
YAP1 is a transcriptional coactivator and the principal effector of the Hippo signaling pathway, which is causally implicated in human cancer. Several
Indexed as
Adaptor Proteins, Signal TransducingAnimalsCarcinogenesisCells, CulturedGene Expression RegulationHumansMiceNeoplasms, ExperimentalNuclear Localization SignalsNucleotide MotifsOncogene Proteins, FusionProteasome Endopeptidase ComplexSignal TransductionTranscription FactorsTranscription, GeneticAdaptor Proteins, Signal TransducingNuclear Localization SignalsOncogene Proteins, FusionProteasome Endopeptidase ComplexTranscription Factorsangiosarcomacancerependymomagene fusionMAMLD1SS18TEADTFE3verteporfinYAP1
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