Evidence map›Paper›PMID 32675240›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system.

Rajiv A Mohan, Fernanda M Bosada, Jan H van Weerd, Karel van Duijvenboden, Jianan Wang, Mathilda T M Mommersteeg, Ingeborg B Hooijkaas, Vincent Wakker, Corrie de Gier-de Vries, Ruben Coronel and 5 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. CoordinatedeLife · 2025
    Article
  8. Immune-mediated cardiac development and regeneration.Seminars in cell & developmental biology · 2025
    Review
  9. Epigenetic Mechanisms in Heart Diseases.Reviews in cardiovascular medicine · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Development of the Cardiac Conduction System.Advances in experimental medicine and biology · 2024
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Modeling Human Cardiac Arrhythmias: Insights from Zebrafish.Journal of cardiovascular development and disease · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Rajiv A MohanDepartment of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-3622-1759
Fernanda M BosadaDepartment of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Jan H van WeerdDepartment of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Karel van DuijvenbodenDepartment of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Jianan WangDepartment of Clinical and Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Mathilda T M MommersteegBurdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom.ORCID 0000-0001-6624-3038
Ingeborg B HooijkaasDepartment of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-7236-7627
Vincent WakkerDepartment of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-5490-7447
Corrie de Gier-de VriesDepartment of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-6272-5961
Ruben CoronelDepartment of Clinical and Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-9433-6119
Gerard J J BoinkDepartment of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-6592-5106
Jeroen BakkersHubrecht Institute and University Medical Center Utrecht, 3584 CT Utrecht, the Netherlands.ORCID 0000-0002-9418-0422
Phil BarnettDepartment of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Bas J BoukensDepartment of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Vincent M ChristoffelsDepartment of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands; v.m.christoffels@amsterdamumc.nl.ORCID 0000-0003-4131-2636
Amsterdam University Medical Centers · NLUniversity Medical Center Utrecht · NLUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome-wide association studies have identified noncoding variants near

Indexed as

Atrioventricular NodeT-Box Domain ProteinsAnimalsArrhythmias, CardiacCalcium Channels, T-TypeMiceMice, TransgenicMutationRyanodine Receptor Calcium Release ChannelTranscriptomeCacna1g protein, mouseCalcium Channels, T-Typeryanodine receptor 2. mouseRyanodine Receptor Calcium Release ChannelT-Box Domain ProteinsTbx3 protein, mouseatrioventricular conduction systemCacna1gelectrical patterningRyr2Tbx3

Identifiers

PMID32675240
PMCPMC7414162
OpenAlexW3042543031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.