Evidence map›Paper›PMID 32675085›Full record

ArticleImmunoHorizons2020

Transcriptomic Analysis Reveals Receptor Subclass-Specific Immune Regulation of CD8

Claire Mazahery, Saba Valadkhan, Alan D Levine

Open access · goldAbstract read
In one paragraph

Article in ImmunoHorizons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Claire MazaheryDepartment of Pathology, Case Western Reserve University, Cleveland, OH 44106.ORCID 0000-0002-9950-5433
Saba ValadkhanDepartment of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH 44106.ORCID 0000-0002-6859-4883
Alan D LevineDepartment of Pathology, Case Western Reserve University, Cleveland, OH 44106; alan.levine@case.edu.ORCID 0000-0002-5706-0667
Case Western Reserve University · US

Funding

WG3: HIV, Co-infections and Co-morbiditiesP30AI036219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI Immaculate Lillian Nankya · 1994 to 2026
$50.0M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007250 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI HUANG, ALEX YEE-CHEN · 1985 to 2023
$33.4M
Identification of immune protective pathways dysregulated by opioid use in HIV infection, using a systems biology-based approach, toward the goal of pharmacological restoration of immune functionR01DA043253 · NIDA · CASE WESTERN RESERVE UNIVERSITY · PI LEVINE, ALAN DAVID · 2016 to 2021
$4.3M
Immunology Training Program-PredoctoralT32AI089474 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI COBB, BRIAN A · 2010 to 2025
$3.4M
Defining the lncRNA-mediated cis regulatory networks that control HIV life cycle in T cellsR21AI127252 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI VALADKHAN, SABA · 2016 to 2017
$436k
NIAID NIH HHS P30 AI036219NIAID NIH HHS R21 AI127252NIAID NIH HHS T32 AI089474NIDA NIH HHS R01 DA043253NIGMS NIH HHS T32 GM007250
6 · The paper itself

Abstract

Opioid peptides are released at sites of injury, and their cognate G protein-coupled opioid receptors (OR) are expressed on immune cells. Exposure of human circulating CD8

Indexed as

Analgesics, OpioidCD8-Positive T-LymphocytesHumansLipid MetabolismReceptors, Opioid, muSignal TransductionTranscriptomeAnalgesics, OpioidReceptors, Opioid, mu

Identifiers

PMID32675085
PMCPMC8236285
OpenAlexW3042723832

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.