Evidence map›Paper›PMID 32674781›Full record

ArticleAnalytica chimica acta2020

Microfluidic-RT-LAMP chip for the point-of-care detection of emerging and re-emerging enteric coronaviruses in swine.

Ling Zhou, Yonghui Chen, Xueen Fang, Yanhong Liu, Mengkan Du, Xiandong Lu, Qianniu Li, Yuan Sun, Jingyun Ma, Tian Lan

Abstract read
In one paragraph

Article in Analytica chimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Research Advances on Swine Acute Diarrhea Syndrome Coronavirus.Animals : an open access journal from MDPI · 2024
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Application of Microfluidics for Bacterial Identification.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ling ZhouCollege of Animal Science, South China Agricultural University, 483 Wushan Road, Guangzhou, 510000, China.
Yonghui ChenCollege of Animal Science, South China Agricultural University, 483 Wushan Road, Guangzhou, 510000, China.
Xueen FangDepartment of Chemistry and Institutes of Biomedical Sciences, Fudan University, 2005 Songhu Road, Shanghai, 200433, China.
Yanhong LiuNingbo IGene Technology Co., Ltd, 688 JinDa Road, Ningbo, 315100, China.
Mengkan DuXiaoshan Bureau of Animal Husbandry and Veterinary, 528 XiaoRan Road, Hangzhou, 311200, China.
Xiandong LuNingbo IGene Technology Co., Ltd, 688 JinDa Road, Ningbo, 315100, China.
Qianniu LiCollege of Animal Science, South China Agricultural University, 483 Wushan Road, Guangzhou, 510000, China.
Yuan SunCollege of Animal Science, South China Agricultural University, 483 Wushan Road, Guangzhou, 510000, China.
Jingyun MaCollege of Animal Science, South China Agricultural University, 483 Wushan Road, Guangzhou, 510000, China. Electronic address: majy2400@scau.edu.cn.
Tian LanCollege of Animal Science, South China Agricultural University, 483 Wushan Road, Guangzhou, 510000, China. Electronic address: lantian2016@scau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and swine acute diarrhea syndrome-coronavirus (SADS-CoV) are three emerging and re-emerging coronaviruses (CoVs). Symptoms caused by these three viruses are extremely similar, including acute diarrhea, vomiting and even death in piglets. To date, strict biosecurity is still the most effective disease prevention and control measures, and the early detection of pathogens is the most important link. Here, we developed a microfluidic-RT-LAMP chip detection system for the first time, which could detected PEDV, PDCoV and SADS-CoV simultaneously, and had advantages of rapid, simple, sensitive, high-throughput, and accurate at point-of-care settings. The lowest detection limits of the microfluidic-RT-LAMP chip method are 10

Indexed as

AlphacoronavirusAnimalsCoronavirusDiarrheaFecesLab-On-A-Chip DevicesLimit of DetectionNucleic Acid Amplification TechniquesPoint-of-Care SystemsPorcine epidemic diarrhea virusReproducibility of ResultsRNA, ViralSensitivity and SpecificitySwineRNA, ViralEmerging and re-emerging swine coronavirusesLoop mediated isothermal amplification (LAMP)Microfluidic chipPOC

Identifiers

PMID32674781
PMCPMC7234951

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.