Evidence map›Paper›PMID 32674743›Full record

ArticleThe British journal of nutrition2021

Cruciferous vegetable intake is inversely associated with extensive abdominal aortic calcification in elderly women: a cross-sectional study.

Lauren C Blekkenhorst, Marc Sim, Simone Radavelli-Bagatini, Nicola P Bondonno, Catherine P Bondonno, Amanda Devine, John T Schousboe, Wai H Lim, Douglas P Kiel, Richard J Woodman and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The British journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Lauren C BlekkenhorstSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, WA6027, Australia.ORCID 0000-0003-1561-9052
Marc SimSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, WA6027, Australia.ORCID 0000-0001-5166-0605
Simone Radavelli-BagatiniSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, WA6027, Australia.
Nicola P BondonnoSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, WA6027, Australia.
Catherine P BondonnoSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, WA6027, Australia.
Amanda DevineSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, WA6027, Australia.
John T SchousboePark Nicollet Osteoporosis Centre and HealthPartners Institute, HealthPartners, Minneapolis, MN55416, USA.
Wai H LimMedical School, The University of Western Australia, Perth, WA6000, Australia.
Douglas P KielHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA02215, USA.
Richard J WoodmanFlinders Centre for Epidemiology and Biostatistics, Flinders University, Adelaide, SA5042, Australia.
Jonathan M Hodgson *School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA6027, Australia.
Richard L Prince *Medical School, The University of Western Australia, Perth, WA6000, Australia.
Joshua R Lewis *School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA6027, Australia.
Edith Cowan University · AUThe University of Western Australia · AUBeth Israel Deaconess Medical Center · USFlinders University · AUUniversity of Minnesota · US

Funding

RISK FACTORS FOR VERTEBRAL FRACTURE AND BONE LOSSR01AR041398 · NIAMS · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI KIEL, DOUGLAS P. · 1991 to 2025
$16.1M
NIAMS NIH HHS R01 AR041398
6 · The paper itself

Abstract

We have previously shown that higher intake of cruciferous vegetables is inversely associated with carotid artery intima-media thickness. To further test the hypothesis that an increased consumption of cruciferous vegetables is associated with reduced indicators of structural vascular disease in other areas of the vascular tree, we aimed to investigate the cross-sectional association between cruciferous vegetable intake and extensive calcification in the abdominal aorta. Dietary intake was assessed, using a FFQ, in 684 older women from the Calcium Intake Fracture Outcome Study. Cruciferous vegetables included cabbage, Brussels sprouts, cauliflower and broccoli. Abdominal aortic calcification (AAC) was scored using the Kauppila AAC24 scale on dual-energy X-ray absorptiometry lateral spine images and was categorised as 'not extensive' (0-5) or 'extensive' (≥6). Mean age was 74·9 (sd 2·6) years, median cruciferous vegetable intake was 28·2 (interquartile range 15·0-44·7) g/d and 128/684 (18·7 %) women had extensive AAC scores. Those with higher intakes of cruciferous vegetables (>44·6 g/d) were associated with a 46 % lower odds of having extensive AAC in comparison with those with lower intakes (<15·0 g/d) after adjustment for lifestyle, dietary and CVD risk factors (ORQ4 v. Q1 0·54, 95 % CI 0·30, 0·97, P = 0·036). Total vegetable intake and each of the other vegetable types were not related to extensive AAC (P > 0·05 for all). This study strengthens the hypothesis that higher intake of cruciferous vegetables may protect against vascular calcification.

Indexed as

BrassicaBrassicaceaeElder Nutritional Physiological PhenomenaVegetablesAbsorptiometry, PhotonAgedAorta, AbdominalCross-Sectional StudiesDiet SurveysEatingEnergy IntakeFemaleHumansVascular CalcificationAbdominal aortic calcificationArteriosclerosisAtherosclerosisCruciferous vegetablesVascular calcificationVegetablesWomen

Identifiers

PMID32674743
PMCPMC7844610
OpenAlexW3042469192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.