ReviewCurrent cardiology reviews2021
Left Ventricular Noncompaction: New Insights into a Poorly Understood Disease.
Review in Current cardiology reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Left ventricular excessive trabeculation: pathophysiology, diagnostic challenges, and prognostic significance.Heart failure reviews · 2026Review
- Left Ventricular Hypertrabeculation and Ventricular Arrhythmias.Journal of clinical medicine · 2026Article
- Left Ventricular Non-Compaction Cardiomyopathy: The Tragedies & Trabeculations of the Architectural Cardiac Sponge.Journal of clinical medicine · 2026Review
- Optimizing the Diagnostic Assessment of Left Ventricular Noncompaction Cardiomyopathy: The Clinical Value of Cardiac Magnetic Resonance Imaging.Current medical imaging · 2025Article
- Aortic Valve Annular Characteristics in Isolated Left Ventricular Non-Compaction-Detailed Analysis from the Three-Dimensional Speckle Tracking Echocardiographic MAGYAR-Path Study.Journal of clinical medicine · 2025Article
- Inherited Hypertrabeculation? Genetic and Clinical Insights in Blood Relatives of Genetically Affected Left Ventricular Excessive Trabeculation Patients.Life (Basel, Switzerland) · 2025Article
- Non-compaction of the ventricular myocardium associated with large patent ductus arteriosus: primary or secondary?BMC cardiovascular disorders · 2024Article
- Catheter Ablation of Left Ventricular Summit Ectopies in Left Ventricular Noncompaction.Journal of medical cases · 2023Article
- A novel mutation in the TTN gene resulted in left ventricular noncompaction: a case report and literature review.BMC cardiovascular disorders · 2023Review
- Recommendations for the Management of Cardiomyopathy Mutation Carriers: Evidence, Doubts, and Intentions.Journal of clinical medicine · 2023Review
- Unusual Evolution of Hypertrophic Cardiomyopathy in Non-Compaction Myocardium in a Pompe Disease Patient.Journal of clinical medicine · 2023Article
- Article
- Tricuspid Annular Abnormalities in Isolated Left Ventricular Non-compaction-Insights From the Three-dimensional Speckle-Tracking Echocardiographic MAGYAR-Path Study.Frontiers in cardiovascular medicine · 2022Article
- Overlap phenotypes of the left ventricular noncompaction and hypertrophic cardiomyopathy with complex arrhythmias and heart failure induced by the novel truncated DSC2 mutation.Orphanet journal of rare diseases · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Left ventricular noncompaction (LVNC) is a congenital pathology that directly affects the lining walls of myocardial tissue, causing trabeculations with blood filling in the inner wall of the heart, concomitantly with the development of a mesocardial thinning. Although LVNC was described for the first time as long ago as 1984, our understanding of the disease with regard to its genetic pattern, diagnosis, clinical presentation and treatment is still scanty. LVNC can present as an isolated condition or associated with congenital heart disease, genetic syndromes or neuromuscular disease. This suggests that LVNC is not a distinct form of cardiomyopathy, but rather a morphological expression of different diseases. Recognition of the disease is of fundamental importance because its clinical manifestations are variable, ranging from the absence of any symptom to congestive heart failure, lethal arrhythmias and thromboembolic events. The study of this disease has emphasized its genetic aspects, as it may be of sporadic origin or hereditary, in which case it most commonly has an autosomal dominant inheritance or one linked to the X chromosome. Echocardiography is the gold standard for diagnosis, and magnetic resonance imaging may refine the identification of the disease, especially in those patients with non-conclusive echocardiography. This article sets out to review the main characteristics of LVNC and present updates, especially in the genetic pattern, diagnosis and treatment of the disease.
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