Evidence map›Paper›PMID 32674684›Full record

ArticleJournal of dental research2020

Y Y Sweat, M Sweat, W Yu, M Sanz-Navarro, L Zhang, Z Sun, S Eliason, O D Klein, F Michon, Z Chen and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Genetic architecture of craniofacial morphogenesis: roles ofFrontiers in cell and developmental biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Y Y SweatDepartment of Anatomy and Cell Biology, The University of Iowa, Iowa City, IA, USA.
M SweatDepartment of Anatomy and Cell Biology, The University of Iowa, Iowa City, IA, USA.ORCID 0000-0002-5400-1266
W YuDepartment of Anatomy and Cell Biology, The University of Iowa, Iowa City, IA, USA.
M Sanz-NavarroDevelopmental Biology Program, Institute of Biotechnology, University of Helsinki, Helsinki, Finland.
L ZhangBinzhou Medical University, Yantai, China.
Z SunDepartment of Anatomy and Cell Biology, The University of Iowa, Iowa City, IA, USA.
S EliasonDepartment of Anatomy and Cell Biology, The University of Iowa, Iowa City, IA, USA.
O D KleinDepartment of Orofacial Sciences and Program in Craniofacial Biology, University of California-San Francisco, San Francisco, CA, USA.
F MichonDevelopmental Biology Program, Institute of Biotechnology, University of Helsinki, Helsinki, Finland.
Z ChenState Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine of Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.ORCID 0000-0003-2095-1324
B A AmendtDepartment of Anatomy and Cell Biology, The University of Iowa, Iowa City, IA, USA.
University of Iowa · USUniversity of Helsinki · FIBinzhou Medical University · CNUniversity of California, San Francisco · USWuhan University · CN

Funding

University of Iowa Institutional Training Program in Oral Health ResearchT90DE023520 · NIDCR · UNIVERSITY OF IOWA · PI STEVEN M. LEVY · 2013 to 2026
$5.6M
Molecular Mechanisms of PITX2 During Craniofacial DevelopmentR01DE013941 · NIDCR · UNIVERSITY OF TULSA · PI AMENDT, BRAD A · 2000 to 2013
$4.2M
Co-opting Lef-1 and miR-26b activities to regulate dental stem cells and their progenyR01DE028527 · NIDCR · UNIVERSITY OF IOWA · PI AMENDT, BRAD A, CAO, HUOJUN · 2020 to 2024
$2.1M
Oral and Craniofacial Bone Regeneration using MicroRNA ModulationR01DE026433 · NIDCR · UNIVERSITY OF IOWA · PI AMENDT, BRAD A, HONG, LIU · 2017 to 2021
$1.8M
A microRNA-based Approach for Bone RegenerationR21DE025328 · NIDCR · UNIVERSITY OF IOWA · PI HONG, LIU · 2016 to 2017
$410k
New Biotechnology using MicroRNA Inhibitors to Regenerate Alveolar BoneR43DE027569 · NIDCR · NATUREMIRI, LLC · PI SANDRA, ALEXANDER · 2018 to 2018
$225k
Hybrid 3D bioprinting of bone using microRNA-based bioinkR03EB025873 · NIBIB · UNIVERSITY OF IOWA · PI AMENDT, BRAD A · 2018 to 2019
$153k
NIBIB NIH HHS R03 EB025873NIDCR NIH HHS R01 DE013941NIDCR NIH HHS R01 DE026433NIDCR NIH HHS R01 DE028527NIDCR NIH HHS R21 DE025328NIDCR NIH HHS R43 DE027569NIDCR NIH HHS T90 DE023520
6 · The paper itself

Abstract

In humans, ankyloglossia and cleft palate are common congenital craniofacial anomalies, and these are regulated by a complex gene regulatory network. Understanding the genetic underpinnings of ankyloglossia and cleft palate will be an important step toward rational treatment of these complex anomalies. We inactivated the Sry (sex-determining region Y)-box 2 (

Indexed as

Cleft PalateEpitheliumGene Expression Regulation, DevelopmentalHumansMouth MucosaPalateSignal TransductionSOXB1 Transcription FactorsSOX2 protein, humanSOXB1 Transcription Factorsankyloglossiacleft palatecraniofacial anomalyoral epitheliumpalate rugaetooth agenesis

Identifiers

PMID32674684
PMCPMC7580171
OpenAlexW3043103177

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.