Evidence map›Paper›PMID 32674373›Full record

ArticleGenes2020

A New Strategy to Increase Production of Genoprotective Bioactive Molecules from Cotyledon-Derived

Dina Gad, Mahmoud Elhaak, Andrea Pompa, Magdy Mattar, Mohamed Zayed, Daniele Fraternale, Karl-Josef Dietz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Efficacy and Mechanisms ofCurrent rheumatology reviews · 2024
    Pooled it
  2. Hepatoprotective effects of silybin in liver fibrosis.World journal of gastroenterology · 2025
    Review
  3. Potential antibacterial and antioxidant inhibitory activities ofSaudi journal of biological sciences · 2023
    Article
  4. Review
  5. Bioconversion of Callus-Produced Precursors to Silymarin Derivatives inInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dina GadBiochemistry and Physiology of Plants, Faculty of Biology W5, Bielefeld University, 33501 Bielefeld, Germany.ORCID 0000-0002-8561-9093
Mahmoud ElhaakFaculty of Science, Botany Department, Tanta University, Tanta, Egypt.
Andrea PompaDepartment of Biomolecular Sciences, University of Urbino "Carlo Bo" Via Donato Bramante, 28, 61029 Urbino (PU), Italy.
Magdy MattarFaculty of Science, Botany Department, Menoufia University, Shebin EL-koum, Egypt.
Mohamed ZayedFaculty of Science, Botany Department, Menoufia University, Shebin EL-koum, Egypt.
Daniele FraternaleDepartment of Biomolecular Sciences, University of Urbino "Carlo Bo" Via Donato Bramante, 28, 61029 Urbino (PU), Italy.ORCID 0000-0002-8489-4747
Karl-Josef DietzBiochemistry and Physiology of Plants, Faculty of Biology W5, Bielefeld University, 33501 Bielefeld, Germany.ORCID 0000-0003-0311-2182

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a need to enhance the production of bioactive secondary metabolites and to establish new production systems, e.g., for liver-protective compounds of

Indexed as

AntioxidantsAsparagineBenzyl CompoundsChromatography, High Pressure LiquidCotyledonEgyptFlavonoidsInositolPhytochemicalsPurinesSeedsSilybum marianumSilymarinSpectrometry, Mass, Electrospray IonizationAntioxidantsAsparaginebenzylaminopurineBenzyl CompoundsFlavonoidsInositolPhytochemicalsPurinesSilymarin3,5-O-dicaffeoylquinic acid6-benzylaminopurineAmes testasparaginecallus inductionchlorogenic acidgenotoxicitySilybum marianumsilymarin

Identifiers

PMID32674373
PMCPMC7396986

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.