Evidence map›Paper›PMID 32674367›Full record

ReviewCells2020

Inflammation in Parkinson's Disease: Mechanisms and Therapeutic Implications.

Marta Pajares, Ana I Rojo, Gina Manda, Lisardo Boscá, Antonio Cuadrado

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06977204 (Role of Physical Activity on Neuroinflammation in Parkinson's Disease), which is not on this map. Cited by 423 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
423citing papers in PubMed, 5 pooled it
31.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06977204 recruitingnot on this mapstarted 2023, after this paper: background citation

Role of Physical Activity on Neuroinflammation in Parkinson's Disease

TypeobservationalSponsorIRCCS National Neurological Institute "C. Mondino" FoundationRan2023 to 2026Enrolled40ConditionsParkinson Disease, Physical Inactivity, Physical Disability
3 · Its place in the literature

Who cites it

423 citing papers in PubMed, 5 syntheses or guidelines pooled it, 734 citations in OpenAlex.

  1. Pooled it
  2. Physical exercise and inflammation in Parkinson's disease: a review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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363 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Marta PajaresInstituto de Investigaciones Biomédicas "Alberto Sols" UAM-CSIC, 28029 Madrid, Spain.
Ana I RojoInstituto de Investigaciones Biomédicas "Alberto Sols" UAM-CSIC, 28029 Madrid, Spain.
Gina MandaDepartment Cellular and Molecular Medicine, Victor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Lisardo BoscáInstituto de Investigaciones Biomédicas "Alberto Sols" UAM-CSIC, 28029 Madrid, Spain.
Antonio CuadradoInstituto de Investigaciones Biomédicas "Alberto Sols" UAM-CSIC, 28029 Madrid, Spain.
Instituto de Salud Carlos III · ESInstitutul National Victor Babes · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized by the death of dopaminergic neurons that project from the substantia nigra

Indexed as

AnimalsBlood-Brain BarrierHumansImmunomodulationInflammationMicrogliaParkinson DiseaseTranscription, Geneticimmune systemneurodegenerationneuroinflammationParkinson’s diseasetherapy

Identifiers

PMID32674367
PMCPMC7408280
OpenAlexW3042580583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.