Evidence map›Paper›PMID 32674253›Full record

ArticleAnimals : an open access journal from MDPI2020

Differential Transcription of Selected Cytokine and Neuroactive Ligand-receptor Genes in Peripheral Leukocytes from Calves in Response to Cautery Disbudding.

Kavitha Kongara, Venkata Sayoji Rao Dukkipati, Hui Min Tai, Axel Heiser, Alan Murray, James Webster, Craig Brian Johnson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Pain Mitigation Strategies for Disbudding in Goat Kids.Animals : an open access journal from MDPI · 2024
    Review
  2. Pain Assessment in Goat Kids: Focus on Disbudding.Animals : an open access journal from MDPI · 2023
    Review
  3. The profile of inflammatory factors in dairy calves withVeterinary research forum : an international quarterly journal · 2022
    Article
  4. Refinements to Animal Models for Biomedical Research.Animals : an open access journal from MDPI · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kavitha KongaraSchool of Veterinary Science, Massey University, Palmerston North 4410, New Zealand.
Venkata Sayoji Rao DukkipatiSchool of Veterinary Science, Massey University, Palmerston North 4410, New Zealand.ORCID 0000-0002-1835-593X
Hui Min TaiTown and Country Vets, 257 Great South Road, Drury, Auckland 2113, New Zealand.
Axel HeiserSchool of Veterinary Science, Massey University, Palmerston North 4410, New Zealand.ORCID 0000-0003-0389-6132
Alan MurraySchool of Veterinary Science, Massey University, Palmerston North 4410, New Zealand.
James WebsterAgResearch, Ruakura, Hamilton 3214, New Zealand.
Craig Brian JohnsonSchool of Veterinary Science, Massey University, Palmerston North 4410, New Zealand.
Massey University · NZAgResearch · NZStatistics New Zealand · NZ

Funding

undefined <span style="color:gray;font-size:10px;">undefined</span> N/A
6 · The paper itself

Abstract

Calf disbudding is a painful husbandry practice on dairy and beef cattle farms. An objective measurement of pain is useful to reliably evaluate the pain intensity and anti-nociceptive (analgesic) efficacy of therapeutic agents. The aim of this study was to investigate the changes in peripheral leucocyte inflammatory cytokine gene expression in calves after disbudding, and to assess whether the changes in cytokine gene expression could be an indicator of the efficacy of analgesic drugs. In a randomised controlled study, 16 calves (aged 31 to 41 days and weighing 58 to 73 kg), undergoing routine disbudding, were randomly allocated into two groups (

Indexed as

calvescytokinesdisbuddinggene transcriptionmeloxicamnCounterpain

Identifiers

PMID32674253
PMCPMC7401531
OpenAlexW3042159871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.