ArticleAesthetic surgery journal2021
The Prevalence of Self-Reported Health Complaints and Health-Related Quality of Life in Women With Breast Implants.
Article in Aesthetic surgery journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Breast Implant Illness: Symptoms, Outcomes with Explantation and Potential Etiologies-A Systematic Review and Meta-analysis.Aesthetic plastic surgery · 2025Pooled it
- Clinical Outcomes in Women with Breast Implant Illness After Removal Surgery: Experience from a Latin American Center.Aesthetic plastic surgery · 2026Observational
- Breast implant illness after reconstruction with silicone breast implants.Journal of the National Cancer Institute · 2025Article
- Defining Breast Implant Illness: A Systematic Review and Meta-analysis of Patient-reported Symptoms.Plastic and reconstructive surgery. Global open · 2025Article
- Clinical Characteristics of ASIA Syndrome in Patients with Silicone Breast Implants: A Scoping Review.World journal of plastic surgery · 2025Review
- Recognizing and Managing Breast Implant Complications: A Review for Healthcare Providers Who Treat Women Who Underwent Breast Implant-Based Surgery.International journal of women's health · 2025Review
- Medical Specialist Care Utilization Prior to the Explantation of Cosmetic Silicone Breast Implants: A Nationwide Retrospective Data Linkage Study.Aesthetic plastic surgery · 2024Article
- Patient Satisfaction Using BREAST-Q and Breast Implant Illness after Breast Reconstruction in Transwomen.Plastic and reconstructive surgery. Global open · 2024Article
- Breast Implant Illness May Be Rooted in Mast Cell Activation: A Case-Controlled Retrospective Analysis.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024Article
- Neuroimaging in Breast Implant Illness: An fMRI Pilot Study.Aesthetic surgery journal · 2023Article
- Prevalence of Local Postoperative Complications and Breast Implant Illness in Women With Breast Implants.JAMA network open · 2022Article
- Effects of Silicone Breast Implants on Human Cell Types In Vitro: A Closer Look on Host and Implant.Aesthetic plastic surgery · 2022Review
- Impact of Capsulectomy Type on Post-Explantation Systemic Symptom Improvement: Findings From the ASERF Systemic Symptoms in Women-Biospecimen Analysis Study: Part 1.Aesthetic surgery journal · 2022Article
- Silicone Particle Migration: A Misleading Report.Aesthetic surgery journal · 2022Article
- Contextualizing Breast Implant Removal Patterns with Google Trends: Big Data Applications in Surgical Demand.Plastic and reconstructive surgery. Global open · 2022Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSome of the millions of women with silicone breast implants (SBIs) report a pattern of systemic complaints, known as ASIA syndrome. However, the association between these complaints and breast implants remains uncertain.
objectivesThis study aimed to evaluate the prevalence of complaints in women with breast implants and healthy controls, and to compare their health-related quality of life.
methodsFour groups of subjects were requested to fill in a general and a diagnostic questionnaire, and the Short Form 36. Group 1 was recruited from the Dutch foundation for breast implant illness (BII). Two groups were recruited from Dutch hospitals, where they had been augmented or reconstructed with SBIs (group 2) or saline-filled and hydrogel implants (group 3). A control group without breast implants was recruited from friends of subjects from group 2.
resultsIn total, 238 women completed the questionnaires. ASIA manifestations appeared in the majority of the respondents (72.3%-98.8%), with a latency period of 0 to 35 years. Adjusted for age, smoking, and comorbidities, typical symptoms only occurred significantly more frequently in group 1. The presence of a chronic disease was an independent predictor for ASIA syndrome. The health-related quality of life was lower in women with SBIs than in women without breast implants.
conclusionsThe adjusted prevalence of BII manifestations is not significantly higher in women with SBIs than in women without implants. The findings of this study suggest that results on BII are subject to selection bias. Further studies are needed to prove an association between self-reported complaints and SBIs. LEVEL OF EVIDENCE: 2:
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