Evidence map›Paper›PMID 32674087›Full record

ArticleJournal of neural engineering2020

i-SATA: A MATLAB based toolbox to estimate current density generated by transcranial direct current stimulation in an individual brain.

Rajan Kashyap, Sagarika Bhattacharjee, Ramaswamy Arumugam, Kenichi Oishi, John E Desmond, Sh Annabel Chen

Open access · greenAbstract read
In one paragraph

Article in Journal of neural engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Rajan KashyapCentre for Research and Development in Learning (CRADLE), Nanyang Technological University, Singapore.ORCID 0000-0002-5967-2173
Sagarika BhattacharjeePsychology, School of Social Sciences (SSS), Nanyang Technological University, Singapore.
Ramaswamy ArumugamCentre for Research and Development in Learning (CRADLE), Nanyang Technological University, Singapore.
Kenichi OishiThe Johns Hopkins University School of Medicine, Baltimore, United States of America.
John E DesmondThe Johns Hopkins University School of Medicine, Baltimore, United States of America.
Sh Annabel ChenCentre for Research and Development in Learning (CRADLE), Nanyang Technological University, Singapore.
Nanyang Technological University · SGJohns Hopkins University · US

Funding

Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI S. Ali Fatemi, Bradley L Schlaggar · 2020 to 2026
$9.9M
Translational Neuroscience CoreU54HD079123 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI FATEMI, S. ALI, SCHLAGGAR, BRADLEY L · 2014 to 2019
$7.9M
NICHD NIH HHS P50 HD103538NICHD NIH HHS U54 HD079123
6 · The paper itself

Abstract

objectiveTranscranial Direct Current Stimulation (tDCS) is a technique where a weak current is passed through the electrodes placed on the scalp. The distribution of the electric current induced in the brain due to tDCS is provided by simulation toolbox like Realistic volumetric Approach based Simulator for Transcranial electric stimulation (ROAST). However, the procedure to estimate the total current density induced at the target and the intermediary region of the cortex is complex. The Systematic-Approach-for-tDCS-Analysis (SATA) was developed to overcome this problem. However, SATA is limited to standardized (MNI152) headspace only. Here we develop individual-SATA (i-SATA) to extend it to individual head. APPROACH: T1-weighted images of 15 subjects were taken from two Magnetic Resonance Imaging scanners of different strengths. Across the subjects, the montages were simulated in ROAST. i-SATA converts the ROAST output to Talairach space. The x, y and z coordinates of the anterior commissure (AC), posterior commissure (PC), and Mid-Sagittal (MS) points are necessary for the conversion. AC and PC are detected using the acpcdetect toolbox. We developed a method to determine the MS in the image and cross-verified its location manually using BrainSight®. MAIN

resultsDetermination of points with i-SATA is fast and accurate. The i-SATA provided estimates of the current-density induced across an individual's cortical lobes and gyri as tested on images from two different scanners. SIGNIFICANCE: Researchers can use i-SATA for customizing tDCS-montages. With i-SATA it is also easier to compute the inter-individual variation in current-density across the target and intermediary regions of the brain. The software is publicly available.

Indexed as

Transcranial Direct Current StimulationBrainElectrodesHeadHumansMagnetic Resonance ImagingSuccinimidesSulfidesN-hydroxysuccinimide S-acetylthioacetateSuccinimidesSulfides

Identifiers

PMID32674087
PMCPMC8114188
OpenAlexW3043756027

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.