Evidence map›Paper›PMID 32674008›Full record

ReviewCurrent opinion in structural biology2020

Structural insights into DNA loop extrusion by SMC protein complexes.

Sumanjit Datta, Léa Lecomte, Christian H Haering

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in structural biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. DNA segment capture by Smc5/6 holocomplexes.Nature structural & molecular biology · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Mitotic chromosomes.Seminars in cell & developmental biology · 2021
    Review
  9. Article
  10. Review
  11. DNA Manipulation and Single-Molecule Imaging.Molecules (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sumanjit DattaEuropean Molecular Biology Laboratory (EMBL), Meyerhofstr. 1, 69117 Heidelberg, Germany; Collaboration for joint PhD degree between EMBL and Heidelberg University, Faculty of Biosciences, Germany.
Léa LecomteEuropean Molecular Biology Laboratory (EMBL), Meyerhofstr. 1, 69117 Heidelberg, Germany; Collaboration for joint PhD degree between EMBL and Heidelberg University, Faculty of Biosciences, Germany.
Christian H HaeringEuropean Molecular Biology Laboratory (EMBL), Meyerhofstr. 1, 69117 Heidelberg, Germany; Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany. Electronic address: christian.haering@uni-wuerzburg.de.
European Molecular Biology Organization · DEUniversity of Würzburg · DE

Funding

European Research Council 681365
6 · The paper itself

Abstract

Structural Maintenance of Chromosomes (SMC) protein complexes play key roles in the three-dimensional organization of genomes in all kingdoms of life. Recent insights from chromosome contact mapping experiments and single-molecule imaging assays suggest that these complexes achieve distinct cellular functions by extruding large loops of DNA while they move along the chromatin fiber. In this short review, we summarize recent insights into the molecular architecture of these unconventional DNA motor complexes, their interaction with their DNA substrates, and the remarkable dynamic changes they can undergo during their ATPase reaction cycle.

Indexed as

ChromosomesDNADNA-Binding ProteinsMultiprotein ComplexesBacteriaProtein BindingYeastsDNADNA-Binding ProteinsMultiprotein Complexes

Identifiers

PMID32674008
PMCPMC7612452
OpenAlexW3042477154

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.