ArticlePloS one2020
Comparing feasibility of low-tube-voltage protocol with low-iodine-concentration contrast and high-tube-voltage protocol with high-iodine-concentration contrast in coronary computed tomography angiography.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Radiation and Contrast Medium Dosage Optimization of Coronary CT Angiography While Combining Personalized Patient Protocol Technology and Automated Tube Voltage Selection Technology.Diagnostics (Basel, Switzerland) · 2026Article
- Low- versus high-concentration iodine contrast media for coronary computed tomography angiography and dynamic stress computed tomography perfusion: a study protocol for a prospective randomized trial.Journal of cardiovascular imaging · 2026Article
- Feasibility Study of Triple-low CCTA for Coronary Artery Disease Screening Combining Contrast Enhancement Boost and Deep Learning Reconstruction.Reviews in cardiovascular medicine · 2025Article
- The impact of automatic tube current modulation related settings of a modern GE CT scanner on image quality and patient dose; details do matter.Journal of applied clinical medical physics · 2024Article
- Evaluating the Image Quality of Neck Structures Scanned on Chest CT with Low-Concentration-Iodine Contrast Media.Tomography (Ann Arbor, Mich.) · 2022Article
- An Individualized Contrast-Enhanced Liver Computed Tomography Imaging Protocol Based on Body Mass Index in 126 Patients Seen for Liver Cirrhosis.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
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Authors and funding
4 authors.
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Abstract
backgroundTo investigate the feasibility of a low tube voltage (80 kVp) protocol with low concentration contrast media (CM) (iodixanol 320 mgl/ml) as compared with a high tube voltage (100 kVp) protocol with high concentration CM (iomeprol 400 mgl/ml) in coronary CT angiography (CCTA) for patients with body mass index less than 30. MATERIALS AND
methodsA total of 93 patients were randomly assigned into three groups and underwent CCTA as follows: Group A) 100 kVp, 100-350 mAs, 400 mgl/ml CM at 4ml/s, and reconstructed with filtered back projection; Group B and C) 80 kVp, 100-450 mAs, 320 mgl/ml CM at 4 ml/s and 5 ml/s, respectively and reconstructed with iterative reconstruction. Objective and subjective image quality (IQ) was analyzed.
resultsThe image noise, intravascular attenuation, signal-to-noise ratio and contrast-to-noise ratio of major coronary arteries did not differ significantly among three groups. Subjective IQ analyses on vascular attenuation and image noise did not differ significantly, either (all of p > 0.05). Qualitative IQ of Group B and C was non-inferior to that of Group A. Substantial reduction of radiation exposure was achieved in group B (2.60 ± 0.48 mSv) and C (2.72 ± 0.54 mSv), compared with group A (3.58 ± 0.67 mSv) (p < 0.05).
conclusionCCTA at 80 kVp with 320 mgl/ml CM and iterative reconstruction is feasible, achieving radiation dose reduction, while preserving IQ.
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