ArticlePloS one2020
Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Breast cancer mortality in Argentina, 1991-2023: a nationwide ecological study of spatiotemporal patterns and regional inequalities.Lancet regional health. Americas · 2026Article
- Characterization of forensic DIP-STR markers in the admixed population of Córdoba, Argentina.International journal of legal medicine · 2026Article
- Article
- Unraveling the genetic landscape and admixture dynamics of urban populations across Peru.Communications biology · 2026Article
- High Prevalence of Non-BRCA Pathogenic Variants and a Recurrent PALB2 Variant in an Argentine Hereditary Breast and Ovarian Cancer Cohort.Cancer medicine · 2026Article
- Interactions Between the Gut Microbiome and Genetic and Clinical Risk Factors for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Patients with Type 2 Diabetes Mellitus from Different Geographical Regions of Argentina.Life (Basel, Switzerland) · 2026Article
- Article
- Racial and Gender Discrimination When Tailoring Medical Management to Hypertension Treatment in Latin America.American journal of hypertension · 2025Review
- Peruvian Population Genomics: Unraveling the Genetic Landscape and Admixture Dynamics of Urban Populations.bioRxiv : the preprint server for biology · 2025Article
- Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas.Cell genomics · 2024Article
- The Genomic and Cultural Diversity of the Inka Qhapaq Hucha Ceremony in Chile and Argentina.Genome biology and evolution · 2024Article
- Hemispheric asymmetries in cortical grey matter of gyri and sulci in modern human populations from South America.Journal of anatomy · 2024Article
- Apolipoprotein E Polymorphisms in Andean Population of Jujuy, Argentina.Journal of Alzheimer's disease reports · 2024Article
- Nationwide genetic analysis of more than 600 families with inherited eye diseases in Argentina.NPJ genomic medicine · 2023Article
- COVID-19 patients display changes in lymphocyte subsets with a higher frequency of dysfunctional CD8lo T cells associated with disease severity.Frontiers in immunology · 2023Article
- Ortholog genes from cactophilic Drosophila provide insight into human adaptation to hallucinogenic cacti.Scientific reports · 2022Article
- Connexin 43, Bcl-2, Bax, Ki67, and E-cadherin patterns in oral squamous cell carcinoma and its relationship with GJA1 rs12197797 C/G.Medicina oral, patologia oral y cirugia bucal · 2022Article
- PALB2 germline mutations in a multi-gene panel testing cohort of 1905 breast-ovarian cancer patients in Argentina.Breast cancer research and treatment · 2022Article
- Disentangling Signatures of Selection Before and After European Colonization in Latin Americans.Molecular biology and evolution · 2022Article
- Patagonian sheepdog: Genomic analyses trace the footprints of extinct UK herding dogs to South America.PLoS genetics · 2022Article
Corrections and comments
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Authors and funding
28 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Similarly to other populations across the Americas, Argentinean populations trace back their genetic ancestry into African, European and Native American ancestors, reflecting a complex demographic history with multiple migration and admixture events in pre- and post-colonial times. However, little is known about the sub-continental origins of these three main ancestries. We present new high-throughput genotyping data for 87 admixed individuals across Argentina. This data was combined to previously published data for admixed individuals in the region and then compared to different reference panels specifically built to perform population structure analyses at a sub-continental level. Concerning the Native American ancestry, we could identify four Native American components segregating in modern Argentinean populations. Three of them are also found in modern South American populations and are specifically represented in Central Andes, Central Chile/Patagonia, and Subtropical and Tropical Forests geographic areas. The fourth component might be specific to the Central Western region of Argentina, and it is not well represented in any genomic data from the literature. As for the European and African ancestries, we confirmed previous results about origins from Southern Europe, Western and Central Western Africa, and we provide evidences for the presence of Northern European and Eastern African ancestries.
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