Evidence map›Paper›PMID 32673176›Full record

ArticleMolecular biology of the cell2020

Kinetochore proteins suppress neuronal microtubule dynamics and promote dendrite regeneration.

James I Hertzler, Samantha I Simonovitch, Richard M Albertson, Alexis T Weiner, Derek M R Nye, Melissa M Rolls

Open access · bronzeAbstract read
In one paragraph

Article in Molecular biology of the cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

  1. Kinetochore proteins control microtubule dynamics in postmitotic neurons to regulate the formation of dendritic spines.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  3. The conserved fibroblast growth factor receptor-based signaling is required for dendrite regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  18. A photo-switchable assay system for dendrite degeneration and repair inProceedings of the National Academy of Sciences of the United States of America · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

James I HertzlerBiochemistry and Molecular Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802.ORCID 0000-0001-8025-8367
Samantha I SimonovitchBiochemistry and Molecular Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802.ORCID 0000-0002-8288-1619
Richard M AlbertsonBiochemistry and Molecular Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802.ORCID 0000-0003-1382-8053
Alexis T WeinerBiochemistry and Molecular Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802.ORCID 0000-0002-0186-0921
Derek M R NyeBiochemistry and Molecular Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802.ORCID 0000-0003-0539-075X
Melissa M RollsBiochemistry and Molecular Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802.ORCID 0000-0002-5021-4360
Pennsylvania State University · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Using Drosophila Neurons to Identify Mechanisms that Control Microtubule PolarityR01GM085115 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Melissa Rolls · 2010 to 2026
$5.1M
Function of kinetochore proteins in post-mitotic neuronsR21NS117396 · NINDS · PENNSYLVANIA STATE UNIVERSITY, THE · PI ROLLS, MELISSA · 2020 to 2020
$434k
NIGMS NIH HHS R01 GM085115NIH HHS P40 OD018537NINDS NIH HHS R21 NS117396
6 · The paper itself

Abstract

Kinetochores connect centromeric chromatin to spindle microtubules during mitosis. Neurons are postmitotic, so it was surprising to identify transcripts of structural kinetochore (KT) proteins and regulatory chromosome passenger complex (CPC) and spindle assembly checkpoint (SAC) proteins in

Indexed as

Nerve RegenerationAnimalsDendritesDrosophilaDrosophila ProteinsGene Expression RegulationKinetochoresMicrotubule-Associated ProteinsMicrotubulesNerve Tissue ProteinsNeuronsSpindle ApparatusTubulinDrosophila ProteinsMicrotubule-Associated ProteinsNerve Tissue ProteinsTubulin

Identifiers

PMID32673176
PMCPMC7530905
OpenAlexW3042978653

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.