Evidence map›Paper›PMID 32672885›Full record

ArticlePediatric blood & cancer2020

Continuous infusion chemotherapy, radiotherapy, and FDG-PET are feasible during extracorporeal membrane oxygenation.

Seth J Rotz, Francisco A Almeida, Shlomo Koyfman, Sudhir Krishnan, Guramrinder Singh Thind, William Phillips, James Yun, Anthony Zembillas, Mark Zahniser, Alejandro Bribriesco

Open access · greenAbstract readCase Reports
In one paragraph

Article in Pediatric blood & cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Seth J RotzDepartment of Pediatric Hematology, Oncology, and Blood and Marrow Transplantation, Cleveland Clinic Children's Hospital, Cleveland, Ohio.ORCID 0000-0003-2896-1113
Francisco A AlmeidaDepartment of Pulmonary Medicine, Cleveland Clinic, Cleveland, Ohio.
Shlomo KoyfmanDepartment of Radiation Oncology, Cleveland Clinic, Cleveland, Ohio.
Sudhir KrishnanDepartment of Pulmonary Medicine, Cleveland Clinic, Cleveland, Ohio.
Guramrinder Singh ThindDepartment of Critical Care Medicine, Cleveland Clinic, Cleveland, Ohio.
William PhillipsDepartment of Cardiothoracic Anesthesia, Cleveland Clinic, Cleveland, Ohio.
James YunDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Anthony ZembillasDepartment of Pediatric Hematology, Oncology, and Blood and Marrow Transplantation, Cleveland Clinic Children's Hospital, Cleveland, Ohio.
Mark ZahniserDepartment of Cardiothoracic Anesthesia, Cleveland Clinic, Cleveland, Ohio.
Alejandro BribriescoDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Cleveland Clinic · US

Funding

Institutional Career Development CoreKL2TR002547 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI DWEIK, RAED A. · 2018 to 2022
$7.7M
NCATS NIH HHS KL2 TR002547
6 · The paper itself

Abstract

Extracorporeal membrane oxygenation (ECMO) may be used in extreme circumstances for patients with a mediastinal mass and respiratory failure. We report on a young man with primary mediastinal B-cell lymphoma invading into the trachea, requiring a 40-day ECMO run who underwent fluorodeoxyglucose positron emission tomography (FDG-PET) imaging and treatment with concurrent mediastinal irradiation and continuous infusion chemotherapy while on this life-saving technology. This case illustrates that oncology patients may be managed by multidisciplinary teams for extended periods in extraordinary circumstances using multimodality therapies. Additionally, to our knowledge this is the first case to demonstrate the feasibility of FDG-PET imaging while on ECMO.

Indexed as

ChemoradiotherapyExtracorporeal Membrane OxygenationLymphoma, B-CellMediastinal NeoplasmsPositron-Emission TomographyAdolescentFluorodeoxyglucose F18HumansMaleFluorodeoxyglucose F18chemotherapyDA-EPOCH-RECMOmediastinal massPETradiation

Identifiers

PMID32672885
PMCPMC7699825
OpenAlexW3042830795

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.