ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2020
Chronic Corticosteroid Use as a Risk Factor for Perioperative Complications in Patients Undergoing Total Joint Arthroplasty.
Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- The significance of perioperative glucocorticoids in the prevention of seroma formation after mastectomies: a systematic review and meta-analysis.Breast cancer research and treatment · 2025Pooled it
- A systematic review and meta-analysis comparing outcomes following total knee arthroplasty for rheumatoid arthritis versus for osteoarthritis.BMC musculoskeletal disorders · 2023Pooled it
- After total hip arthroplasty, patients with glucocorticoid-treated osteonecrosis of the femoral head have a higher risk of in-hospital reoperation: a nationwide propensity score-matched analysis.International orthopaedics · 2026Article
- Risks and Management of Glucocorticoid Therapy for Patients with Rheumatic Disease Having Surgery.Current rheumatology reports · 2026Review
- Maintenance Inhaled Corticosteroid Use is Associated With Increased Revision Risk in Asthmatic Patients Undergoing Lumbar Fusion.Global spine journal · 2026Article
- Association of preoperative corticosteroids with persistent opioid requirements following total knee arthroplasty: an exploratory population-based cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Article
- Are Preoperative Corticosteroid Injections in Large or Intermediate Joints Associated with Surgical Site Infection After Soft Tissue Hand Surgery? A Retrospective Database Analysis.The Journal of hand surgery · 2025Article
- Administration of a Methylprednisolone Taper and Complication Rates Following Total Knee Arthroplasty: A Multicenter Retrospective Study.Arthroplasty today · 2025Article
- Chronic preoperative steroid use and total shoulder arthroplasty: a propensity score matched analysis of early-onset infectious outcomes.Arthroplasty (London, England) · 2025Article
- Chronic corticosteroid use does not increase short-term complications following carpometacarpal arthroplasty.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- Association of Preoperative Opioid and Glucocorticoid Use With Mortality and Complication After Total Knee or Hip Arthroplasty.Journal of Korean medical science · 2024Article
- Incidence of postoperative pneumonia in various surgical subspecialties: a retrospective study.Annals of medicine and surgery (2012) · 2024Article
- Reasons and Risk Factors for Same-Day Discharge Following Total Joint Arthroplasty: A Systematic Review.Arthroplasty today · 2024Article
- Impact of Perioperative Dexamethasone Administration on Infection and Implant Osseointegration in a Preclinical Model of Orthopedic Device-Related Infection.Microorganisms · 2024Article
- Article
- Analysis of complications and revisions after spine surgery in 270 multiple myeloma patients with spinal involvement.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Chronic Steroid Use, Complications, and Readmission Following Open Reduction Internal Fixation of Distal Radius Fracture.Journal of hand surgery global online · 2023Article
- Effects of Preoperative Chronic Steroid Use on Postoperative Outcomes in Orthopedic Surgery: A Systematic Review and Meta-Analysis.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Chronic steroid use as a risk factor for postoperative complications following arthroscopic rotator cuff repair.JSES international · 2023Article
- Identifying Risk Factors for Complication and Readmission with Same-Day Discharge Arthroplasty.The Journal of arthroplasty · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteoarthritis may be caused by or concurrent with diseases such as rheumatoid arthritis or systemic lupus erythematosus, which rely on chronic corticosteroids regimens for treatment. If a total knee or hip arthroplasty is needed, this chronic treatment method has been associated with poorer surgical outcomes.
methodsA retrospective analysis of data collected by the American College of Surgeons National Surgical Quality Improvement Program was conducted. The Current Procedural Terminology codes were used to identify 403,566 total knee arthroplasty and total hip arthroplasty patients who were then stratified by the use of chronic corticosteroids for univariate analysis.
resultsForteen thousand seven hundred seventy-four of the patients identified were prescribed chronic corticosteroid regimens. A statistically significant difference was observed in perioperative complications for patients prescribed with corticosteroids, including higher rates of surgical site infection (P = 0.0001), occurrence of deep incisional surgical site infection (P < 0.0001), occurrences of organ space surgical site infection (P < 0.0001), wound dehiscence (P < 0.0001), general would infection (P < 0.0001), pneumonia (P < 0.0001), occurrences of unplanned intubation (P = 0.0002), urinary tract infection (P < 0.0001), and readmission (P < 0.0001). No statistically significant difference was observed in the 30-day mortality between the 2 groups (0.63), venous thromboembolic event (0.42), cerebrovascular accident (0.12), myocardial infarction (0.49), cardiac arrest (0.098), deep vein thrombosis (0.17), or sepsis (0.52).
conclusionMany of the notable differences in complications may be directly attributed to the immunosuppressive nature of corticosteroids. With increased knowledge of which perioperative complications to monitor, surgeons can tailor treatment strategies to this population that reduce morbidity and improve outcomes.
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