ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2020
Vitamin D and sleep in children.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Severe Vitamin D Deficiency-A Possible Cause of Resistance to Treatment in Psychiatric Pathology.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Vitamin D Supplementation and Sleep: A Systematic Review and Meta-Analysis of Intervention Studies.Nutrients · 2022Pooled it
- The Role of Vitamin D in Sleep Disorders of Children and Adolescents: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Sleep Duration and Sun Exposure in Portuguese Children: Associations With Obesity Indicators.American journal of human biology : the official journal of the Human Biology Council · 2026Article
- Psychopathological correlates of early childhood sleep terror: associations with nutritional biomarkers, behavioral dysregulation, and sleep disturbance.BMC psychiatry · 2026Article
- Vitamin D as a Regulator of the Biological Clock-Implications for Circadian-Metabolic Dysregulation.International journal of molecular sciences · 2026Review
- Vitamin D and Mean Platelet Volume as Biomarkers in Pediatric Obstructive Sleep Apnea: Associations with Disease Severity and Sleep Parameters.Journal of clinical medicine · 2026Article
- Vitamin D and Sleep Disorders.Advances in experimental medicine and biology · 2026Review
- [Observation and analysis of Vitamin D levels in 147 children undergoing adenoidectomy and/or tonsillectomy].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025Article
- Do not sleep on vitamin D: vitamin D is associated with sleep variability in apparently healthy adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Research advances in children's sleep and vitamin D levels.Annals of pediatric endocrinology & metabolism · 2025Article
- Vitamin D insufficiency and sleep disturbances in children with ADHD: a case-control study.Frontiers in psychiatry · 2025Article
- Association between Serum Vitamin D Status and Circadian Syndrome: A Cross-Sectional Study.Nutrients · 2024Article
- Oral nutritional supplementation with dietary counseling improves linear catch-up growth and health outcomes in children with or at risk of undernutrition: a randomized controlled trial.Frontiers in nutrition · 2024Article
- The Mediation Role of Sleep Disturbances between Vitamin D and Depressive Symptoms: A Cross-Sectional Study.Brain sciences · 2023Article
- The association between vitamin D status and sleep duration in school-aged children; the CASPIAN-V study.Journal of diabetes and metabolic disorders · 2023Article
- [Cross-sectional study on the sleep status and risk factors for sleep problems in infants and young children in Jilin Province].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- Relationships between 25-Hydroxyvitamin D Levels and Obstructive Sleep Apnea Severity in Children: An Observational Study.Journal of clinical medicine · 2023Article
- A review article on neuroprotective, immunomodulatory, and anti-inflammatory role of vitamin-D3 in elderly COVID-19 patients.The Egyptian journal of neurology, psychiatry and neurosurgery · 2023Review
- Vitamin D deficiency promoting non-24 h sleep-wake disorder: a case report.Frontiers in neurology · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesThe impact of vitamin D on human health including sleep has been well described in adults. Its deficiency has been associated with multiple sleep disorders such as decrease in sleep duration, worsening of sleep quality, and even OSA. Such correlation is less evident in the pediatric population. In the current study, we examined the relationship between sleep architecture and vitamin D status in children referred to a sleep clinic.
methodsThis was a retrospective-cohort study in a tertiary care children's hospital over a 1-year period. Children who underwent an in-laboratory overnight-polysomnogram and had a 25-hydroxy vitamin D level obtained within 120 days of the sleep study were included. Patients with OSA or central sleep apnea were excluded. Data from polysomnograms and Pediatric Sleep Questionnaires were collected and analyzed.
resultsA total of 39 patients (mean age, 6.6 years; 46% female) were included in the study. Twenty (51%) patients had vitamin D deficiency (25-hydroxy vitamin D level < 30 ng/mL). Children with vitamin D deficiency had less total sleep time (470.3 minutes ± 35.6 vs 420.3 minutes ± 61.7; P = .004) and poorer sleep efficiency (91.9% ± 5.6% vs 84.5% ± 9.5%; P = .015) compared with children with sufficient vitamin D. In addition, children with vitamin D deficiency had later weekday bedtimes (21:02 Pm ± 1:01 vs 20:19 Pm ± 0:55; P = .037) and later weekend bedtimes (21:42 Pm ± 0:59 vs 20:47 Pm ± 1:08; P = .016) than children with sufficient vitamin D, with a tendency for later wake time that did not reach statistical significance. The remainder of the polysomnogram findings and Pediatric Sleep Questionnaire data were not different between the 2 groups.
conclusionsVitamin D deficiency in children was associated with objectively measured decreased sleep duration and poorer sleep efficiency. Furthermore, vitamin D deficiency was associated with delayed bedtimes, suggesting that vitamin D and circadian rhythm could be related. Future prospective studies in children would be helpful to learn if vitamin D deficiency leads to sleep disturbance or vice versa.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.