Evidence map›Paper›PMID 32672090›Full record

ArticleNeurocase2020

Dementia with Lewy bodies presenting as Logopenic variant primary progressive Aphasia.

Samuel Boes, Hugo Botha, Mary Machulda, Val Lowe, Jonathan Graff-Radford, Jennifer L Whitwell, Rene L Utianski, Joseph R Duffy, Keith A Josephs

Open access · greenAbstract readCase Reports
In one paragraph

Article in Neurocase, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Primary Progressive Aphasia: Toward a Pathophysiological Synthesis.Current neurology and neuroscience reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Samuel BoesDepartment of Neurology, Mayo Clinic , Rochester, Minnesota, USA.
Hugo BothaDepartment of Neurology, Mayo Clinic , Rochester, Minnesota, USA.
Mary MachuldaDepartment of Psychiatry and Psychology, Mayo Clinic , Rochester, Minnesota, USA.
Val LoweDepartment of Radiology, Mayo Clinic , Rochester, Minnesota, USA.
Jonathan Graff-RadfordDepartment of Neurology, Mayo Clinic , Rochester, Minnesota, USA.
Jennifer L WhitwellDepartment of Radiology, Mayo Clinic , Rochester, Minnesota, USA.
Rene L UtianskiDepartment of Neurology, Mayo Clinic , Rochester, Minnesota, USA.
Joseph R DuffyDepartment of Neurology, Mayo Clinic , Rochester, Minnesota, USA.
Keith A JosephsDepartment of Neurology, Mayo Clinic , Rochester, Minnesota, USA.
Mayo Clinic · US

Funding

Molecular and structural imaging in atypical Alzheimer's disease: a longitudinal studyR01AG050603 · NIA · MAYO CLINIC ROCHESTER · PI WHITWELL, JENNIFER LOUISE · 2016 to 2025
$5.9M
PIB PET Scanning in Speech and Language Based DementiasR01DC010367 · NIDCD · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A · 2010 to 2014
$1.7M
NIA NIH HHS R01 AG050603NIDCD NIH HHS R01 DC010367
6 · The paper itself

Abstract

We report a patient presenting with clinical features of logopenic variant primary progressive aphasia (lvPPA) who was later diagnosed with probable dementia with Lewy bodies. LvPPA is a neurodegenerative disease that is characterized by anomia, word-finding difficulty, impaired comprehension, and phonological errors. The most common underlying pathology for lvPPA is Alzheimer's disease. However, our patient with clinical features of logopenic progressive aphasia was later diagnosed with probable dementia with Lewy bodies. This case demonstrates that lvPPA can also be an initial manifestation of a phenotype of dementia with Lewy bodies.

Indexed as

AgedAniline CompoundsAphasia, Primary ProgressiveHumansLewy Body DiseaseMagnetic Resonance ImagingMaleNeuropsychological TestsPositron-Emission TomographyThiazoles2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazoleAniline CompoundsThiazolesalzheimer diseasebeta-amyloid (Aβ)dementia with Lewy bodiesLogopenic progressive aphasia

Identifiers

PMID32672090
PMCPMC7530001
OpenAlexW3043101589

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.