Evidence map›Paper›PMID 32671996›Full record

Trial reportCancer reports (Hoboken, N.J.)2020

A feasibility study of a psycho-educational support intervention for men with prostate cancer on active surveillance.

John G Hughes, Geraldine M Leydon, Sam Watts, Stephanie Hughes, Lucy A Brindle, Emily Arden-Close, Roger Bacon, Brian Birch, Lallita Carballo, Hilary Plant and 5 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Cancer reports (Hoboken, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 2 countries.

John G HughesRoyal London Hospital for Integrated Medicine, University College London Hospitals NHS Trust, London, UK.ORCID 0000-0002-4513-2395
Geraldine M LeydonDepartment of Primary Care and Population Sciences, University of Southampton, Southampton, UK.
Sam WattsDepartment of Primary Care and Population Sciences, University of Southampton, Southampton, UK.
Stephanie HughesDepartment of Primary Care and Population Sciences, University of Southampton, Southampton, UK.
Lucy A BrindleSchool of Health Sciences, University of Southampton, Southampton, UK.
Emily Arden-CloseDepartment of Psychology, Bournemouth University, Poole, UK.
Roger BaconPatient Representative, UK.
Brian BirchUniversity Hospital Southampton and School of Medicine, University of Southampton, Southampton, UK.
Lallita CarballoMacmillan Support and Information Service, University College London Hospitals, London, UK.
Hilary PlantMacmillan Support and Information Service, University College London Hospitals, London, UK.
Caroline M MooreDivision of Surgery and Interventional Science, University College London, London, UK.
Beth StuartDepartment of Primary Care and Population Sciences, University of Southampton, Southampton, UK.
Guiqing YaoDepartment of Health Sciences, University of Leicester, Leicester, UK.
George LewithDepartment of Primary Care, University of Southampton, Southampton, UK.
Alison RichardsonSchool of Health Sciences, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Southampton City Council · GBMacmillan Cancer Support · GBBournemouth University · GBRoyal London Hospital for Integrated Medicine · GBSouthampton Hospital · USUniversity College London · GBUniversity College London Hospitals NHS Foundation Trust · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Leicester · GBUniversity of Southampton · GB

Funding

Prostate Cancer UK PG14-023
6 · The paper itself

Abstract

backgroundPROACTIVE is a psycho-educational support intervention for prostate cancer patients managed on Active Surveillance. PROACTIVE is composed of two interdependent components: group workshops and internet-delivered information modules.

aimsWe conducted a feasibility study to determine the practicality of delivering PROACTIVE at two prostate cancer centres. METHODS AND

resultsThe feasibility study was a mixed-methods randomized parallel-group exploratory trial. Participants were randomised using a ratio of 3:1 PROACTIVE group to treatment as usual. Qualitative semi-structured interviews and quantitative measures were completed at baseline, intervention completion (week 6), and at 6-month follow-up. Interview transcripts were analysed thematically using Framework analysis. Descriptive statistics were used to examine recruitment and retention rates and changing trends in outcome measures. Most aspects of the research design and PROACTIVE intervention were acceptable to those participating in the study. In particular, participants valued the opportunity to share and discuss experiences with other prostate cancer patients on Active Surveillance and receive detailed authoritative information. However, three issues were identified: (a) a low response rate (13 participants recruited, response rate 16%), (b) low utilisation of internet delivered information modules, (c) self-perceived low levels of anxiety amongst participants with the majority perceiving their cancer as not impacting on their day-to-day life or causing anxiety.

conclusionsDue to these significant research design issues, it is not recommended PROACTIVE be evaluated in a large-scale randomised controlled trial. Further research is required to explore the impact of Active Surveillance on anxiety amongst men with localized prostate cancer managed by Active Surveillance.

Indexed as

AgedAnxietyFeasibility StudiesHumansMaleMiddle AgedMotivationOutcome Assessment, Health CarePatient Education as TopicProstatic NeoplasmsActive Surveillanceanxietyfeasibility studyprostate cancerpsycho-educational support

Identifiers

PMID32671996
PMCPMC7941569
OpenAlexW2996564168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.