Evidence map›Paper›PMID 32671810›Full record

ArticleJournal of neurovirology2020

Disseminated cortical and subcortical lesions in neonatal enterovirus 71 encephalitis.

Ryoko Nakamura, Pin Fee Chong, Kohei Haraguchi, Harutaka Katano, Keiko Tanaka-Taya, Ryutaro Kira

Abstract readCase Reports
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In one paragraph

Article in Journal of neurovirology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Expert consensus on the clinical practice of neonatal brain magnetic resonance imaging.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ryoko NakamuraDepartment of Pediatric Neurology, Fukuoka Children's Hospital, 5-1-1 Kashiiteriha Higashi-ku, Fukuoka, 813-0017, Japan.
Pin Fee ChongDepartment of Pediatric Neurology, Fukuoka Children's Hospital, 5-1-1 Kashiiteriha Higashi-ku, Fukuoka, 813-0017, Japan. chong.p.f@fcho.jp.
Kohei HaraguchiDepartment of Pediatric Neurology, Fukuoka Children's Hospital, 5-1-1 Kashiiteriha Higashi-ku, Fukuoka, 813-0017, Japan.
Harutaka KatanoDepartment of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.
Keiko Tanaka-TayaInfectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan.
Ryutaro KiraDepartment of Pediatric Neurology, Fukuoka Children's Hospital, 5-1-1 Kashiiteriha Higashi-ku, Fukuoka, 813-0017, Japan.
Fukuoka Children's Hospital and Medical Center for Infectious Diseases · JPNational Institute of Infectious Diseases · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteroviruses are one of the most important causes of viral encephalitis in the neonatal period. However, the non-specificity of the symptoms presented renders its diagnosis challenging. Intracranial MRI has been reported to be a very useful imaging modality that can detect the characteristic white matter lesions around the periventricular regions. In this study, we report a case of a patient with neonatal encephalitis who presented with normal white blood cell counts in the initial cerebrospinal fluid analysis. A lumbar puncture retap identified pleocytosis, and polymerase chain reaction assays detected enterovirus 71 in the blood and stool samples. Furthermore, MRI revealed atypical disseminated cortical and subcortical white matter lesions on diffusion weighted images, and neuroradiological re-evaluation showed necrotic changes 2 weeks later. This unique case expands our knowledge of the spectrum of neurological disorders due to enterovirus 71 infection in neonatal period.

Indexed as

AcyclovirAntiviral AgentsCerebral CortexDiffusion Magnetic Resonance ImagingEncephalitis, ViralEnterovirus A, HumanEnterovirus InfectionsHumansInfant, NewbornMaleNeuroimagingSpinal PunctureWhite MatterAcyclovirAntiviral AgentsDisseminated subcortical lesionsEnterovirus 71Neonatal encephalitisWhite matter

Identifiers

PMID32671810
OpenAlexW3043797644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.