Evidence map›Paper›PMID 32671614›Full record

SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2020

The prevalence and clinical characteristics of thoracic spinal stenosis: a systematic review.

Guanghui Chen, Tianqi Fan, Xiaoxi Yang, Chuiguo Sun, Dongwei Fan, Zhongqiang Chen

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 3 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Prevalence, diagnosis, and impact on clinical outcomes of dural ossification in the thoracic ossification of the ligamentum flavum: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Pooled it
  3. Should asymptomatic cervical stenosis be treated in the setting of progressive thoracic myelopathy? A systematic review of the literature.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Pooled it
  4. Biomechanical comparison of laminoplasty and in-site regrafting versus laminectomy with pedicle screw fixation for localized thoracic pathological ossification of the ligamentum flavum: a finite element analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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  6. Thoracic ossification of the ligamentum flavum in elite athletes: a case series with surgical outcomes and return-to-play profiles.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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  10. Review
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  14. Reversible intraoperative neuromonitoring changes in thoracic ossification of the posterior longitudinal ligament and/or ossification of the ligamentum flavum surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  15. Review
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  19. [Short-term effectiveness of floating island laminectomy surgery for thoracic spinal stenosis and myelopathy caused by ossification of ligamentum flavum].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Guanghui ChenDepartment of Orthopedics, Peking University Third Hospital, Peking University, #38 Xueyuan Road, Beijing, 1000191, China.ORCID 0000-0001-6031-0180
Tianqi FanDepartment of Orthopedics, Peking University Third Hospital, Peking University, #38 Xueyuan Road, Beijing, 1000191, China.
Xiaoxi YangDepartment of Orthopedics, Peking University Third Hospital, Peking University, #38 Xueyuan Road, Beijing, 1000191, China.
Chuiguo SunDepartment of Orthopedics, Peking University Third Hospital, Peking University, #38 Xueyuan Road, Beijing, 1000191, China.
Dongwei FanDepartment of Orthopedics, Peking University Third Hospital, Peking University, #38 Xueyuan Road, Beijing, 1000191, China.
Zhongqiang ChenDepartment of Orthopedics, Peking University Third Hospital, Peking University, #38 Xueyuan Road, Beijing, 1000191, China. puth_czq@126.com.
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThoracic spinal stenosis (TSS) is a rare disease secondary to multiple pathological changes that differ in prevalence and clinical characteristics. The epidemiological characteristics of these pathologies are largely unknown due to the limited case samples and regional differences. Therefore, a systematic review was conducted to elucidate the prevalence and clinical characteristics of TSS.

methodsCase series and case reports on the ossification of the posterior longitudinal ligaments (OPLL), ossification of the ligamentum flavum (OLF) and thoracic disk herniation (TDH) were screened from PubMed, Embase and Web of Science databases and systematically reviewed. Epidemiological, demographic and segmental distribution data were extracted and analyzed.

resultsA total of 129 studies including 1935 subjects were selected, of which 361 (18.7%) were diagnosed with OPLL, 804 (41.5%) with OLF, 143 (7.4%) with OPLL + OLF and 627 (32.4%) with TDH. Most reports were from China, Japan and USA. Thoracic OPLL occurred mostly at the middle-thoracic spine (43.4%), while OLF predominately occurred at the lower-thoracic spine (63.1%). TDH was mainly localized in the middle (46.0%) and lower-thoracic (50.3%) spine. Thirty-two studies involving 524 patients described tandem spinal stenosis, of which 52.1% had accompanying cervical diseases and 35.9% lumbar diseases.

conclusionsThere are significant differences in the age, sex and segment distribution characteristics of different pathologies leading to TSS. Tandem spinal stenosis is not uncommon and should be considered when diagnosing TSS. Our findings provide new insights into the prevalence and clinical characteristics of TSS and can help reduce misdiagnosis.

Indexed as

Ligamentum FlavumOssification, HeterotopicOssification of Posterior Longitudinal LigamentSpinal StenosisChinaHumansJapanPrevalenceThoracic VertebraeOssification of the ligamentum flavumOssification of the posterior longitudinal ligamentsThoracic disk herniationThoracic spinal stenosis

Identifiers

PMID32671614
OpenAlexW3043348896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.