SynthesisInternational ophthalmology2020
Clinical outcomes of corneal refractive surgery comparing centration on the corneal vertex with the pupil center: a meta-analysis.
Synthesis in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Comparison of asymmetric and symmetric offset ablation in myopic astigmatism patients.Scientific reports · 2025Trial
- Orthokeratology Decentration: Topography Alignment, Tear Profile Symmetry and Induced HOAs.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Impact of Pupil-Decentration on Visual and Refractive Outcomes in Myopic Patients Undergoing High Astigmatic PRK Surgery.Journal of clinical medicine · 2025Article
- Digital Pupillometry and Centroid Shift Changes in Dominant and Nondominant Eyes.Klinische Monatsblatter fur Augenheilkunde · 2025Article
- Comparison of asymmetric offset versus pupil centered ablation in refractive surgery.International journal of ophthalmology · 2025Article
- Comparison of visual outcomes and optical aberrations after SMILE with intraoperative Kappa angle adjustments between small and large Kappa angles.Scientific reports · 2024Article
- Comparative visual outcomes of the first versus second eye following small-incision lenticule extraction (SMILE).BMC ophthalmology · 2024Article
- Comparison of Scheimpflug tomography, Placido disc, and combined Placido Scheimpflug in the measurement of pupil offset in myopic population.Frontiers in medicine · 2024Article
- Effect of preoperative pupil offset on corneal higher-order aberrations after femtosecond laser-assisted in situ keratomileusis.BMC ophthalmology · 2023Article
- Twelve-month outcomes of single-step transepithelial photorefractive keratectomy for moderate hyperopia and hyperopic astigmatism.Eye and vision (London, England) · 2023Article
- Laser-based refractive surgery techniques to treat myopia in adults. An overview of systematic reviews and meta-analyses.Acta ophthalmologica · 2022Review
- Characteristics of Pupil Offset in Young Asian Adults With Mild-Moderate and High Myopia.Translational vision science & technology · 2022Article
- Translation model for CW chord to angle Alpha derived from a Monte-Carlo simulation based on raytracing.PloS one · 2022Article
- The relationship between angle kappa and astigmatism after phacoemulsification with implanting of spherical and aspheric intraocular lens.Indian journal of ophthalmology · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
purposeTo compare the visual and refractive outcomes between centration on the corneal vertex and the pupil center in corneal refractive surgery.
methodsA comprehensive literature search was conducted using PubMed, MEDLINE, EMBASE, and the Cochrane Library to identify relevant studies. The primary outcomes were the postoperative spherical equivalent (SE), effectiveness [uncorrected distance visual acuity (UDVA) ≥ 20/20, eyes within ± 0.50 diopter (D) of target refraction], and safety [loss ≥ 2 lines of corrected distance visual acuity (CDVA)]. Higher-order aberrations were considered secondary outcomes.
resultsSeven studies describing a total of 1964 eyes were included in this meta-analysis. A statistical significance in postoperative SE was found between the two centration methods for the correction of myopia that favor the CV-centered method (p < 0.001). No significant differences were observed in the proportion of eyes with UDVA ≥ 20/20 or loss ≥ 2 lines of CDVA postoperatively. However, the proportion of eyes within ± 0.50 D was slightly higher (p = 0.02) and the coma aberration was much lower in the corneal vertex-centered method (p < 0.001).
conclusionPreferable visual and refractive outcomes could be achieved with either centering on the corneal vertex or pupil center in corneal refractive surgery; however, the corneal vertex-centered method has shown partial benefits in some clinical indices. In order to obtain higher quality of clinical evidences, more randomized controlled trials (RCTs) are required in further investigations.
Indexed as
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Registered trials
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