Evidence map›Paper›PMID 32671551›Full record

SynthesisGeneral thoracic and cardiovascular surgery2021

A meta-analysis comparing transaxillary and transaortic transcatheter aortic valve replacement.

Yong Zhan, Serena Lofftus, Masashi Kawabori, Avneet Soin, Frederick Y Chen

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in General thoracic and cardiovascular surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yong ZhanDivision of Cardiac Surgery, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, #266, Boston, MA, 02111, USA. yzhan@tuftsmedicalcenter.org.ORCID http://orcid.org/0000-0003-4144-9915
Serena LofftusDivision of Cardiac Surgery, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, #266, Boston, MA, 02111, USA.
Masashi KawaboriDivision of Cardiac Surgery, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, #266, Boston, MA, 02111, USA.
Avneet SoinDivision of Cardiac Surgery, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, #266, Boston, MA, 02111, USA.
Frederick Y ChenDivision of Cardiac Surgery, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, #266, Boston, MA, 02111, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe alternative access route of choice for transcatheter aortic valve replacement (TAVR) remains to be elucidated due to lack of evidences. We performed a meta-analysis comparing the outcomes of two common alternative access routes, transaxillary (TAx) and transaortic (TAo) approaches.

methodsThe PubMed/MEDLINE, Embase, and Cochrane library from inception to December 2018 were searched to identify the articles reporting data on both TAx-TAVR and TAo-TAVR. Patients' baseline characteristics, procedural outcomes, and clinical outcomes were extracted from the articles and pooled for analysis.

resultsFour studies, a total of 750 (374 TAo and 376 TAx) patients were included in the study. The two groups were similar in patients' baseline characteristics, although the TAx group comprised few female patients. The two groups differ in outcomes including 30-day mortality, rates of pacemaker implant and acute kidney injury, and length of hospital stay. There were no differences between the two groups with regard to device success, paravalvular leak, stroke, vascular complications, and 1-year mortality.

conclusionCompared with the TAo approach, the TAx approach is associated with favorable short-term mortality, lower incidence of acute kidney injury, and shorter length of hospital stay, but increased pacemaker requirement. TAx could be considered over TAo as the preferred alternative access for TAVR.

Indexed as

Aortic Valve StenosisHeart Valve ProsthesisTranscatheter Aortic Valve ReplacementAortic ValveFemaleHumansRisk FactorsTime FactorsTreatment OutcomeMeta-analysisTransaorticTransaxillaryTranscatheter aortic valve replacement

Identifiers

PMID32671551

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.