Evidence map›Paper›PMID 32671412›Full record

ArticleJournal of molecular medicine (Berlin, Germany)2020

TNFSF13 upregulation confers chemotherapeutic resistance via triggering autophagy initiation in triple-negative breast cancer.

Hui-Yu Lin, Chia-Hao Kuei, Hsun-Hua Lee, Che-Hsuan Lin, Yen-Lin Chen, Chi-Long Chen, Yuan-Feng Lin

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular medicine (Berlin, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hui-Yu LinGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, 110, Taipei, Taiwan.
Chia-Hao KueiGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, 110, Taipei, Taiwan.
Hsun-Hua LeeGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, 110, Taipei, Taiwan.
Che-Hsuan LinDepartment of Otolaryngology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Yen-Lin ChenDepartment of Pathology, Cardinal Tien Hospital, School of Medicine, College of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.
Chi-Long ChenGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, 110, Taipei, Taiwan.
Yuan-Feng LinGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, 110, Taipei, Taiwan. d001089012@tmu.edu.tw.ORCID 0000-0003-4456-0766
Fu Jen Catholic University · TWTaipei Medical University Hospital · TWTaipei Medical University-Shuang Ho Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since chemotherapy is a main strategy to treat triple-negative breast cancer (TNBC) patients currently, identifying a biomarker to predict chemotherapeutic responses is urgently needed for patients to avoid suffering through unnecessary chemotherapeutic treatments. Here, we found that the endogenous expression of TNFSF13 in a panel of TNBC cell lines highly correlates with paclitaxel (PTX) and doxorubicin IC

Indexed as

Gene Expression Regulation, NeoplasticApoptosisAutophagyBiomarkers, TumorCell Line, TumorDrug Resistance, NeoplasmFemaleHumansPaclitaxelTriple Negative Breast NeoplasmsTumor Necrosis Factor Ligand Superfamily Member 13Up-RegulationBiomarkers, TumorPaclitaxelTNFSF13 protein, humanTumor Necrosis Factor Ligand Superfamily Member 13AutophagyChemotherapyPaclitaxelTNFSF13Triple-negative breast cancer

Identifiers

PMID32671412
OpenAlexW3043321114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.