Evidence map›Paper›PMID 32671268›Full record

ArticleHeliyon2020

Effects of high-intensity infrasound on liver lipid content of rats.

Gonçalo Martins Pereira, Sofia S Pereira, Madalena Santos, José Brito, Diamantino Freitas, António Oliveira de Carvalho, Artur Águas, Maria João Oliveira, Pedro Oliveira

Abstract read
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gonçalo Martins PereiraCenter for Interdisciplinary Research Egas Moniz (CiiEM), Monte da Caparica, Portugal.
Sofia S PereiraUnidade Multidisciplinar de Investigação Biomédica - UMIB, Universidade do Porto - UP, Porto, Portugal.
Madalena SantosUnidade Multidisciplinar de Investigação Biomédica - UMIB, Universidade do Porto - UP, Porto, Portugal.
José BritoCenter for Interdisciplinary Research Egas Moniz (CiiEM), Monte da Caparica, Portugal.
Diamantino FreitasLaboratory of Acoustics, Faculty of Engineering (FEUP), University of Porto, Porto, Portugal.
António Oliveira de CarvalhoLaboratory of Acoustics, Faculty of Engineering (FEUP), University of Porto, Porto, Portugal.
Artur ÁguasUnidade Multidisciplinar de Investigação Biomédica - UMIB, Universidade do Porto - UP, Porto, Portugal.
Maria João OliveiraUnidade Multidisciplinar de Investigação Biomédica - UMIB, Universidade do Porto - UP, Porto, Portugal.
Pedro OliveiraCenter for Interdisciplinary Research Egas Moniz (CiiEM), Monte da Caparica, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous experimental studies show that exposure to noise with high and audible frequencies causes multiple metabolic alterations, such as increased liver glycogen and triglycerides. However, the effect of exposure to sound with lower frequencies, such as high-intensity infrasound (frequency <20 Hz and sound pressure level >90 dB), on the liver lipid content is still unclear. As such, we aimed to study the effect of exposure to high-intensity infrasound of both normal and glucose intolerant rats on the liver lipid content. For this study, 79 wild-type male Wistar rats were randomly divided into two groups: G1, no treatment, and G2, induced glucose intolerance. Each of these two groups was randomly divided in two subgroups: s (animals kept in silence) and i (animals continuously exposed to high-intensity infrasound noise). At three noise-exposure time-points (1, 6 and 12 weeks) the rats were sacrificed, the liver was excised and hepatic lipids extracted. Data analysis was performed using a two-way ANOVA (p = 0.05). No significant effects due to interactions between the several factors exist on the liver lipid content (p=0.077). Moreover, no significant effects due to infrasound exposure (p=0.407) or glucose tolerance status (p=0.938) were observed. Our study shows that continuous exposure to high-intensity infrasound has no influence on the lipid content of the liver of both normal and glucose intolerant animals. This finding reinforces the need for further experimental studies on the physiological effects of infrasound due to its possible hazardous effects on human health.

Indexed as

DiabetesEndocrine systemEndocrinologyEnvironmental healthGlucose intoleranceHepatobiliary systemInfrasoundLiver lipidsLiver steatosisMetabolic disorderObesityRat

Identifiers

PMID32671268
PMCPMC7338782

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.