Evidence map›Paper›PMID 32671181›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2020

Lower practice effects as a marker of cognitive performance and dementia risk: A literature review.

Roos J Jutten, Evan Grandoit, Nancy S Foldi, Sietske A M Sikkes, Richard N Jones, Seo-Eun Choi, Melissa L Lamar, Diana K N Louden, Joanne Rich, Douglas Tommet and 2 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Observational
  6. Article
  7. Selective associations between cognitive practice effects and reactive balance adaptation in multiple sclerosis.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026
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  19. Practice Effects and Long Delays: A Case Report Exploring a Novel Approach to Detecting Accelerated Long-Term Forgetting.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Roos J JuttenAlzheimer Center Amsterdam Amsterdam Neuroscience Amsterdam UMC Vrije Universiteit Amsterdam the Netherlands.
Evan GrandoitNorthwestern University Evanston Illinois USA.
Nancy S FoldiQueens College and The Graduate Center of The City University of New York Queens New York USA.
Sietske A M SikkesAlzheimer Center Amsterdam Amsterdam Neuroscience Amsterdam UMC Vrije Universiteit Amsterdam the Netherlands.
Richard N JonesWarren Alpert Medical School of Brown University Providence Rhode Island USA.
Seo-Eun ChoiSchool of Medicine University of Washington Seattle Washington USA.
Melissa L LamarRush Alzheimer's Disease Center Rush University Medical Center Chicago Illinois USA.
Diana K N LoudenUniversity Libraries, University of Washington Seattle Washington USA.
Joanne RichUniversity Libraries, University of Washington Seattle Washington USA.
Douglas TommetWarren Alpert Medical School of Brown University Providence Rhode Island USA.
Paul K CraneSchool of Medicine University of Washington Seattle Washington USA.
Laura A RabinBrooklyn College and The Graduate Center of The City University of New York Brooklyn New York USA.

Funding

Translational pharmacoepidemiology: neuroprotection and neurotoxicity of antihypertensives and strong anticholinergicsU19AG066567 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI Christine L MacDonald · 2021 to 2026
$80.4M
Improving Cognitive Outcome Precision & Responsiveness with Modern PsychometricsR01AG029672 · NIA · UNIVERSITY OF WASHINGTON · PI CRANE, PAUL K · 2007 to 2021
$7.0M
Serial position effect as an evidence-based cognitive marker in Alzheimer diseaseSC3GM122662 · NIGMS · QUEENS COLLEGE · PI FOLDI, NANCY SUZANNE · 2017 to 2020
$462k
NIA NIH HHS R01 AG029672NIA NIH HHS U19 AG066567NIGMS NIH HHS SC3 GM122662
6 · The paper itself

Abstract

backgroundPractice effects (PEs) are improvements in performance after repeated exposure to test materials, and typically viewed as a source of bias in repeated cognitive assessments. We aimed to determine whether characterizing PEs could also provide a useful marker of early cognitive decline.

methodsWe conducted a systematic review of the literature, searching PsycInfo (Ebsco) and PubMed databases for articles studying PEs in aging and dementia populations. Articles published between 1920 and 2019 were included.

resultWe identified 259 articles, of which 27 studied PEs as markers of cognitive performance. These studies consistently showed that smaller, less-robust PEs were associated with current diagnostic status and/or future cognitive decline. In addition, lower PEs were associated with Alzheimer's disease risk factors and neurodegeneration biomarkers.

conclusionPEs provide a potentially useful marker of cognitive decline, and could prove valuable as part of a cost-effective strategy to select individuals who are at-risk for dementia for future interventions.

Indexed as

Alzheimer's diseasecognitionlearning effectspractice effectsretest effects

Identifiers

PMID32671181
PMCPMC7346865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.