ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020
Body-Integrated, Enzyme-Triggered Degradable, Silk-Based Mechanical Sensors for Customized Health/Fitness Monitoring and In Situ Treatment.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 120 citations in OpenAlex.
- Wearable bioelectronics enabled by conductive hydrogels: From materials innovation to clinical translation.Materials today. Bio · 2026Review
- Photonic Nanomaterials for Wearable Health Solutions.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Bidirectional mechanisms and emerging strategies for implantable bioelectronic interfaces.Bioactive materials · 2025Review
- Deep Learning-Assisted Organogel Pressure Sensor for Alphabet Recognition and Bio-Mechanical Motion Monitoring.Nano-micro letters · 2025Article
- Breakthrough Assembly of a Silk Fibroin Composite for Application in Resistive Pressure Sensing.ACS applied polymer materials · 2025Article
- Review
- Advances in Wireless, Batteryless, Implantable Electronics for Real-Time, Continuous Physiological Monitoring.Nano-micro letters · 2023Review
- Review
- Silk-based conductive materials for smart biointerfaces.Smart medicine · 2023Review
- Functional microneedles for wearable electronics.Smart medicine · 2023Review
- High-Performance Strain Sensors Based on Organohydrogel Microsphere Film for Wearable Human-Computer Interfacing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Silk fibroin carriers with sustained release capacity for treating neurological diseases.Frontiers in pharmacology · 2023Review
- Silk fibroin hydrogels for biomedical applications.Smart medicine · 2022Review
- Dissolving Candlelit Microneedle for Chronic Inflammatory Skin Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Synthesis of pH and Glucose Responsive Silk Fibroin Hydrogels.International journal of molecular sciences · 2021Article
- Recent progress in silk fibroin-based flexible electronics.Microsystems & nanoengineering · 2021Review
- Body-Integrated, Enzyme-Triggered Degradable, Silk-Based Mechanical Sensors for Customized Health/Fitness Monitoring and In Situ Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Silk Polymers and Nanoparticles: A Powerful Combination for the Design of Versatile Biomaterials.Frontiers in chemistry · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mechanical signals such as pressure and strain reflect important psychological and physiological states of the human body. Body-integrated sensors, including skin-mounted and surgically implanted ones, allow personalized health monitoring for the general population as well as patients. However, the development of such measuring devices has been hindered by the strict requirements for human-biocompatible materials and the need for high performance sensors; most existing devices or sensors do not meet all the desired specifications. Here, a set of flexible, stretchable, wearable, implantable, and degradable mechanical sensors is reported with excellent mechanical robustness and compliance, outstanding biocompatibility, remotely-triggered degradation, and excellent sensing performance, using a conductive silk fibroin hydrogel (CSFH). They can detect multiple mechanical signals such as pressure, strain, and bending angles. Moreover, combined with a drug-loaded silk-based microneedle array, sensor-equipped devices are shown to be effective for real-time monitoring and in situ treatment of epilepsy in a rodent model. These sensors offer potential applications in custom health monitoring wearables, and in situ treatment of chronic clinical disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.