ReviewCureus2020
Acute Appendicitis Review: Background, Epidemiology, Diagnosis, and Treatment.
Review in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of RIPASA and ALVARADO scores for risk assessment of acute appendicitis: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Effect of Ondansetron on Postoperative Pain and Vomiting after Acute Appendicitis Surgery: A Placebo-Controlled Double-Blinded Randomized Clinical Trial.Pain research & management · 2024Trial
- Deep Learning with Attention Mechanism for Pediatric Appendicitis Detection on Plain Abdominal Radiographs.Journal of imaging informatics in medicine · 2026Article
- Analysis of diagnostic efficacy of serum miR-126-5p levels for stratifying severity in pediatric acute appendicitis.BMC pediatrics · 2026Article
- Suspected Pediatric Appendicitis Management in the Emergency Department: A Prospective Observational Study in an Australian Pediatric Emergency Department.Pediatric emergency care · 2026Observational
- A new score for predicting incidental appendiceal neoplasms in patients aged ≥40 years with acute appendicitis: a multicenter retrospective cohort study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- Article
- Opioid use in postoperative pain management of pediatric appendectomy patients in Japan.Journal of anesthesia · 2025Article
- Simultaneous Acute Appendicitis and Isolated Common Iliac Artery Aneurysm: A Case Report.Clinical case reports · 2025Article
- Delayed Appendectomy Versus Early Intervention: A Systematic Review of Outcomes in Complicated Appendicitis.Cureus · 2025Review
- Epidemiological and histopathological spectrum of gastrointestinal tract disorders: a decade of records from the UAE.BMC gastroenterology · 2025Article
- Preoperative inflammatory markers in pediatric appendicitis: associations with disease severity, postoperative recovery, pain, and surgical outcomes.BMC pediatrics · 2025Article
- Comparison of Gentamicin Saline Solution and Normal Saline in Reducing Surgical Site Infections in Open Appendectomy: A Randomized Controlled Trial.Health science reports · 2025Article
- Utilizing non-invasive biomarkers for early and accurate differentiation of uncomplicated and complicated acute appendicitis: a retrospective cohort analysis.Scientific reports · 2025Article
- Pediatric Appendicitis Score and Ultrasound in children with Acute Appendicitis: An Observational Study.JNMA; journal of the Nepal Medical Association · 2025Observational
- Transumbilical single-site double-port laparoscopic appendectomy in children. Report of a single center experience with comparison with three-port laparoscopic appendectomy.Frontiers in pediatrics · 2025Article
- Trends in visits, imaging, and diagnosis for emergency department abdominal pain presentations in the United States, 2007-2019.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025Article
- Optimization of diagnosis-related groups for patients with acute appendicitis using a machine learning model.Frontiers in public health · 2025Article
- Diagnostic and therapeutic value of appendoscope-assisted endoscopic retrograde appendicitis therapy.Endoscopy international open · 2025Article
- C-reactive protein and digestive pathologies: A narrative review for daily clinical use.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Appendicitis is a common occurrence in both the adult and pediatric populations. The condition most commonly occurs between the ages of 10 and 20 years with a lifetime risk of 8.6% and 6.7% for males and females respectively. Its diagnosis focuses on clinical presentation and imaging modalities classified according to scoring systems such as the Alvarado scoring system. A number of imaging modalities can be used, with CT being the most common one. For acute appendicitis, surgical intervention is considered to be the gold standard of treatment. However, recent research has focused on other modalities of treatment including antibiotics and endoscopic retrograde appendicitis therapy (ERAT) to avoid surgical complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.