ArticleInternational journal of retina and vitreous2020
Identification of epiretinal proliferation in various retinal diseases and vitreoretinal interface disorders.
Article in International journal of retina and vitreous, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Visual and OCT outcomes in epiretinal membrane foveoschisis with and without lamellar macular hole-related diseases.Japanese journal of ophthalmology · 2026Article
- The IGF2-ERK-Fos axis drives a Müller cell glial-mesenchymal transition-like response to disrupt retinal homeostasis in early myopia.Cell communication and signaling : CCS · 2026Article
- Macular Pigment Optical Density Levels Reflect Retinal Remodeling in Lamellar Macular Holes.Investigative ophthalmology & visual science · 2026Observational
- Parafoveal retinal function of epiretinal membrane foveoschisis: a pilot comparison among ERM phenotypes using MP-3 microperimetry.BMC ophthalmology · 2026Article
- Beyond the First Year of Intravitreal Faricimab for Diabetic Macular Oedema: A Single-Centre Experience.Cureus · 2025Article
- Postoperative Outcomes and Prognostic Factors of High Myopia-Epiretinal Membrane Associated with Retinoschisis after Vitrectomy.Ophthalmic research · 2025Article
- Foveal microstructure and visual function in patients with lamellar macular hole, epiretinal membrane foveoschisis or macular pseudohole.Eye (London, England) · 2022Article
- Increased Macrophage-like Cell Density in Retinal Vein Occlusion as Characterized by en Face Optical Coherence Tomography.Journal of clinical medicine · 2022Article
- The clinical and pathogenic significance of atypical epiretinal tissue in macular hole.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Review
- Primary Lamellar Macular Holes: To Vit or Not to Vit.Journal of clinical medicine · 2022Review
- Epiretinal proliferation after rhegmatogenous retinal detachment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- Inner limiting membrane peeling prevents secondary epiretinal membrane after vitrectomy for proliferative diabetic retinopathy.International journal of ophthalmology · 2022Article
- Surgical outcomes in patients with lamellar macular holes selected based on the optical coherence tomography consensus definition.International journal of retina and vitreous · 2021Article
- Multimodal Imaging of Lamellar Macular Holes.Journal of ophthalmology · 2021Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo describe the presence of epiretinal proliferation in eyes with various retinal and vitreoretinal interface conditions.
methodsConsecutive patients seen at the Stein Eye Institute, by one retina specialist, from December 2018 to March 2019, and demonstrating epiretinal proliferation on optical coherence tomography (OCT) were enrolled in this cross-sectional study. Included patients were divided into two groups: vitreoretinal interface pathologies group or retinal diseases group. Presence of epiretinal proliferation and its localization within the 9 macular sectors, as defined by the Early Treatment Diabetic Retinopathy Study (ETDRS), were assessed on OCT.
results77 eyes from 69 patients demonstrated epiretinal proliferation on OCT. The most frequently involved ETDRS sector was the 1-mm central subfield, followed by inner temporal and inner nasal sectors. Localization of epiretinal proliferation correlated with the presence of any retinal abnormalities in the same quadrant (r = 0.962; P < 0.0001). 31 eyes (40.3%) demonstrated symptomatic vitreoretinal interface pathologies including lamellar macular hole, full-thickness macular hole, epiretinal membrane and history of macular peeling. 46 eyes (59.7%) manifested various retinal diseases, including age-related macular degeneration, diabetic retinopathy, refractory macular edema, vein occlusion and high myopia.
conclusionsEpiretinal proliferation was noted in several retinal conditions and not limited only to full-thickness and lamellar macular holes. Different mechanisms affecting retinal homeostasis might trigger Müller cells dysregulation, potentially leading to abnormal retinal remodeling.
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