Evidence map›Paper›PMID 32670559›Full record

ArticleToxicology research2020

The effects of phenanthrene exposure on Treg and Th17 cells related cytokines in female rats.

Haitao Ma, Huizhen Guo, Wenwen Zhang, Fengjing Hu, Yushan Huang, Yong Zeng, Yang Liu, Chengyun Li, Junling Wang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Haitao MaDepartment of Toxicology, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu, China.
Huizhen GuoDepartment of Toxicology, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu, China.
Wenwen ZhangDepartment of Toxicology, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu, China.
Fengjing HuDepartment of Toxicology, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu, China.
Yushan HuangDepartment of Toxicology, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu, China.
Yong ZengDepartment of Toxicology, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu, China.
Yang LiuDepartment of Toxicology, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu, China.
Chengyun LiDepartment of Toxicology, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu, China.
Junling WangDepartment of Toxicology, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu, China.
Lanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenanthrene (Phe) female rat model was established to explore the mechanism of Phe on immune impairment. The rats were randomly divided into three groups, including control (C), low (L), and high (H) groups. Phe was supplied to L and H groups at the dose of 180 and 900 mg/kg orally at first day and with the dose of 90 and 450 mg/kg by intraperitoneal injection at the last 2 days. The C group was enriched with the same volume of corn oil. The liver tissue was collected. Then, the protein and mRNA expressions of interleukin (IL)-35 and the concentration IL-17 were detected to evaluate the function of regulatory T cells (Treg cells) and T helper 17 cells (Th17 cells). In addition, IL-1β and interferon-γ (IFN-γ) were analyzed to evaluate the immune impairment. The results showed that the protein and mRNA expressions of IL-35 decreased significantly in H groups (

Indexed as

femaleinterleukin-17interleukin-35phenanthrene

Identifiers

PMID32670559
PMCPMC7329182
OpenAlexW3025771218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.