Evidence map›Paper›PMID 32670538›Full record

ArticleJournal of tissue engineering

Stiffness-matched biomaterial implants for cell delivery: clinical, intraoperative ultrasound elastography provides a 'target' stiffness for hydrogel synthesis in spinal cord injury.

Jon Prager, Christopher F Adams, Alexander M Delaney, Guillaume Chanoit, John F Tarlton, Liang-Fong Wong, Divya M Chari, Nicolas Granger

Open access · goldAbstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  17. Physical Cues of Matrices Reeducate Nerve Cells.Frontiers in cell and developmental biology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jon PragerBristol Veterinary School, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0003-0488-5478
Christopher F AdamsCellular and Neural Engineering Group, Institute for Science and Technology in Medicine, Keele University, Keele, UK.
Alexander M DelaneyCellular and Neural Engineering Group, Institute for Science and Technology in Medicine, Keele University, Keele, UK.
Guillaume ChanoitBristol Veterinary School, University of Bristol, Bristol, UK.
John F TarltonBristol Veterinary School, University of Bristol, Bristol, UK.
Liang-Fong WongBristol Medical School, University of Bristol, Bristol, UK.
Divya M ChariCellular and Neural Engineering Group, Institute for Science and Technology in Medicine, Keele University, Keele, UK.
Nicolas GrangerThe Royal Veterinary College, University of London, Hatfield, UK.ORCID https://orcid.org/0000-0002-3036-3908
Keele University · GBUniversity of Bristol · GBUniversity of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Safe hydrogel delivery requires stiffness-matching with host tissues to avoid iatrogenic damage and reduce inflammatory reactions. Hydrogel-encapsulated cell delivery is a promising combinatorial approach to spinal cord injury therapy, but a lack of

Indexed as

olfactory ensheathing cell transplantspinal cord elasticitySpinal cord injurystiffness matched hydrogel biomaterialsultrasound elastography

Identifiers

PMID32670538
PMCPMC7336822
OpenAlexW3039731463

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.