ArticleGut pathogens2020
Evaluation of multiplex ARMS-PCR for detection of
Article in Gut pathogens, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06871579 (A Pilot Prospective Study of the Esophageal String Test), which is not on this map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Prospective Study of the Esophageal String Test (EST) for the Diagnosis of Helicobacter Pylori
Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- Synonymous codon-optimized multiplex qPCR for simultaneous detection ofJournal of clinical microbiology · 2026Article
- Phenotypic and genotypic analysis ofFrontiers in cellular and infection microbiology · 2026Article
- Analysis ofInfection and drug resistance · 2026Article
- Methodological evaluation ofFrontiers in cellular and infection microbiology · 2026Article
- Review
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- Prevalence and Variability ofAntibiotics (Basel, Switzerland) · 2025Article
- Antimicrobial drug susceptibility testing for the management ofFrontiers in microbiology · 2025Review
- Clinical evaluation of personalizedFrontiers in cellular and infection microbiology · 2025Observational
- Genetic Markers ofCurrent issues in molecular biology · 2024Article
- Lipopolysaccharide O-antigen profiles of Helicobacter pylori strains from Southwest China.BMC microbiology · 2023Article
- A Chamber-Based Digital PCR Based on a Microfluidic Chip for the Absolute Quantification and Analysis of KRAS Mutation.Biosensors · 2023Article
- Review
- Controlling Gastric Cancer in a World of Heterogeneous Risk.Gastroenterology · 2023Review
- Article
- Helicobacter pylori Infection, Its Laboratory Diagnosis, and Antimicrobial Resistance: a Perspective of Clinical Relevance.Clinical microbiology reviews · 2022Review
- Emphasizing the importance of successful eradication ofAmerican journal of cancer research · 2022Review
- Detection and Treatment ofGastroenterology research and practice · 2022Review
- Molecular testing for H. pylori clarithromycin and quinolone resistance: a prospective Chinese study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Diagnosis ofDiagnostics (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background
resultsIn preliminary studies using a defined number of plasmids with clarithromycin and levofloxacin resistance mutations, the analytical sensitivity of our ARMS-PCR assay was 50 plasmid copies, equating to around 50 bacterium in a gastric biopsy sample. In terms of specificity, the assay was highly specific for the targeted resistance mutations. The assay was also able to reliably and efficiently detect heteroresistance of clarithromycin and levofloxacin mutations, even at a disproportional ratio of 1:1000. From the analysis of 192 samples with suspected
conclusionsOur assay demonstrated high diagnostic sensitivity and specificity for detection of clarithromycin and levofloxacin resistant
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.