Evidence map›Paper›PMID 32670294›Full record

ArticleFrontiers in immunology2020

Identification of a Human

Amalia Lamana, Ricardo Villares, Iria V Seoane, Nuria Andrés, Pilar Lucas, Paul Emery, Edward M Vital, Ana Triguero-Martínez, Ana Marquez, Ana M Ortiz and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. GeneticInternational journal of molecular sciences · 2022
    Article
  9. The Immunogenetics of Alopecia areata.Advances in experimental medicine and biology · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Amalia LamanaRheumatology Service, Instituto de Investigación Sanitaria La Princesa, Hospital Universitario de la Princesa, Madrid, Spain.
Ricardo VillaresDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Iria V SeoaneDepartment of Cellular Biology, Facultad de Biología, Universidad Complutense de Madrid, Madrid, Spain.
Nuria AndrésDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Pilar LucasDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Paul EmeryLeeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), The University of Leeds, Leeds, United Kingdom.
Edward M VitalLeeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), The University of Leeds, Leeds, United Kingdom.
Ana Triguero-MartínezRheumatology Service, Instituto de Investigación Sanitaria La Princesa, Hospital Universitario de la Princesa, Madrid, Spain.
Ana MarquezInstitute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain.
Ana M OrtizRheumatology Service, Instituto de Investigación Sanitaria La Princesa, Hospital Universitario de la Princesa, Madrid, Spain.
Robin MaximeLeeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), The University of Leeds, Leeds, United Kingdom.
Carmen MartínezDepartment of Cellular Biology, Facultad de Biología, Universidad Complutense de Madrid, Madrid, Spain.
Javier MartínInstitute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain.
Rosa P GomarizDepartment of Cellular Biology, Facultad de Biología, Universidad Complutense de Madrid, Madrid, Spain.
Frederique PonchelLeeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), The University of Leeds, Leeds, United Kingdom.
Isidoro González-ÁlvaroRheumatology Service, Instituto de Investigación Sanitaria La Princesa, Hospital Universitario de la Princesa, Madrid, Spain.
Mario MelladoDepartment of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.
Centro Nacional de Biotecnología · ESHospital Universitario de La Princesa · ESUniversidad Complutense de Madrid · ESInstituto de Parasitología y Biomedicina "López - Neyra" · ESNIHR Leeds Musculoskeletal Biomedical Research Unit · GBUniversity of Leeds · GB

Funding

Department of Health CS-2013-13-032Department of Health RTF/01/097Medical Research Council MR/M01665X/1MRF_ MRF-159-0003-ELP-VITAL
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by an autoimmune response in the joints and an exacerbation of cytokine responses. A minority of patients with RA experience spontaneous remission, but most will show moderate/high disease activity, with aggressive joint damage and multiple systemic manifestations. There is thus is a great need to identify prognostic biomarkers for disease risk to improve diagnosis and prognosis, and to inform on the most appropriate therapy. Here we focused on suppressor of cytokine signaling 1 (SOCS1), a physiological negative regulator of cytokines that modulates cell activation. Using four independent cohorts of patients with arthritis, we characterized the correlation between

Indexed as

AdultAgedArthritis, RheumatoidFemaleGenetic MarkersGenetic Predisposition to DiseaseGenotypeHumansMaleMiddle AgedPolymorphism, Single NucleotideSuppressor of Cytokine Signaling 1 ProteinGenetic MarkersSOCS1 protein, humanSuppressor of Cytokine Signaling 1 Proteinbiomarkerscytokinesdisease activityinflammationrheumatoid arthritis

Identifiers

PMID32670294
PMCPMC7332777
OpenAlexW3037859235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.