ArticleNature2020
N
Open access · bronzeAbstract read
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 89 citations in OpenAlex.
- LINE-1 retrotransposons: Multifaceted functions and regulatory mechanisms in health and disease.Molecular therapy. Nucleic acids · 2026Review
- A distinct subclade of AlkB family demethylases in ciliates safeguards the positional fidelity of eukaryotic NProceedings of the National Academy of Sciences of the United States of America · 2026Article
- DNA Adenine Methylation Clock in Brain Aging and Alzheimer's Disease Progression.bioRxiv : the preprint server for biology · 2026Article
- The methyltransferase N6amt1 regulates hippocampal neurogenesis through 6 mA modification of Txnrd3 DNA.Cellular and molecular life sciences : CMLS · 2025Article
- Mechanism for the substrate recognition by a eukaryotic DNA NNature communications · 2025Article
- YTHDF3 recognizes DNA N6-methyladenine and recruits ALKBH1 for 6mA removal from genomic DNA.The EMBO journal · 2025Article
- Microrchidia ATPases and DNA 6mA demethylase ALKBH1 act antagonistically on PRC2 to control chromatin structure and stress tolerance.Nature plants · 2025Article
- SMAC: identifying DNA N6-methyladenine (6mA) at the single-molecule level using SMRT CCS data.Briefings in bioinformatics · 2025Article
- Cap-specific terminal N6-methyladeonsine methylation of RNA mediated by PCIF1 and possible therapeutic implications.Genes & diseases · 2025Review
- ALKBH1: emerging biomarker and therapeutic target for cancer treatment.Discover oncology · 2024Review
- Interrogation of the interplay between DNA N6-methyladenosine (6mA) and hypoxia-induced chromatin accessibility by a randomized empirical model (EnrichShuf).Nucleic acids research · 2024Article
- Selective Effect of DNA N6-Methyladenosine Modification on Transcriptional Genetic Variations in East Asian Samples.International journal of molecular sciences · 2024Article
- Adenosine Deaminase-Like Gene-Carried Lentivirus Toolkit for Identification of DNA NAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Molecular basis of an atypical dsDNA 5mC/6mA bifunctional dioxygenase CcTet from Coprinopsis cinerea in catalyzing dsDNA 5mC demethylation.Nucleic acids research · 2024Article
- Epigenetic marks or not? The discovery of novel DNA modifications in eukaryotes.The Journal of biological chemistry · 2024Review
- The Molecular Basis of Human ALKBH3 Mediated RNA NAngewandte Chemie (International ed. in English) · 2024Article
- Sequencing of NMolecular cell · 2024Article
- 6mA-Sniper: Quantifying 6mA sites in eukaryotes at single-nucleotide resolution.Science advances · 2023Article
- A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature.Genome biology · 2023Article
- Single-nucleus multiomic mapping of mMolecular cell · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 6 institutions in 2 countries.
Zheng Li *Department of Genetics and Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, USA.
Shuai Zhao *MOE Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, China.
Raman V Nelakanti *Department of Genetics and Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-2085-4236
Kaixuan Lin *Department of Genetics and Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, USA.
Tao P Wu *Department of Genetics and Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-9859-4534
Myles H AldermanDepartment of Genetics and Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-8515-1462
Cheng GuoDepartment of Chemistry, University of California, Riverside, CA, USA.ORCID http://orcid.org/0000-0001-6194-1232
Pengcheng WangDepartment of Chemistry, University of California, Riverside, CA, USA.
Min ZhangMOE Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, China.
Wang MinInterdepartmental Program in Vascular Biology and Therapeutics, Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-2479-6096
Zongliang JiangSchool of Animal Sciences, AgCenter, Louisiana State University, Baton Rouge, LA, USA.ORCID http://orcid.org/0000-0002-7473-3210
Yinsheng WangDepartment of Chemistry, University of California, Riverside, CA, USA.ORCID http://orcid.org/0000-0001-5565-283X
Haitao LiMOE Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, China. lht@tsinghua.edu.cn.ORCID http://orcid.org/0000-0001-6741-293X
Andrew Z XiaoDepartment of Genetics and Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, USA. andrew.xiao@yale.edu.ORCID http://orcid.org/0000-0001-6578-8669
Yale Cancer Center · USCenter for Life Sciences · CNUniversity of California, Riverside · USBaylor College of Medicine · USLouisiana State University · USYale University · US
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9MPREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007499 · NIGMS · YALE UNIVERSITY · PI CARLSON, JOHN R, REINKE, VALERIE J · 1985 to 2022
$13.9MChemical Biology of DNA and RNA AlkylationR35ES031707 · NIEHS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Yinsheng Wang · 2020 to 2026
$6.1MDNA Methylation at N6-Adenine in Placental Trophoblast DevelopmentR01HD102533 · NICHD · UNIVERSITY OF FLORIDA · PI JIANG, ZONGLIANG, XIAO, ZHUO ANDREW · 2020 to 2024
$3.1MA novel epigenetic mechanism in early embryogenesisR35GM136346 · NIGMS · YALE UNIVERSITY · PI XIAO, ZHUO ANDREW · 2020 to 2024
$2.5MInvestigate Novel Epigenetic Silencing Mechanisms in Mouse ESCsR01GM114205 · NIGMS · YALE UNIVERSITY · PI XIAO, ZHUO ANDREW · 2015 to 2019
$2.1MNICHD NIH HHS R01 HD102533NIEHS NIH HHS R35 ES031707NIGMS NIH HHS R01 GM114205NIGMS NIH HHS R35 GM136346NIGMS NIH HHS T32 GM007205NIGMS NIH HHS T32 GM007499
Abstract
The recent discovery of N
Indexed as
Embryonic DevelopmentAdenineAnimalsBase PairingDNAEuchromatinFemaleHumansMaleMatrix Attachment Region Binding ProteinsMiceStem CellsThermodynamicsTrophoblasts6-methyladenineAdenineDNAEuchromatinMatrix Attachment Region Binding ProteinsSATB1 protein, human
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.