ArticleNature communications2020
Rieske iron-sulfur protein induces FKBP12.6/RyR2 complex remodeling and subsequent pulmonary hypertension through NF-κB/cyclin D1 pathway.
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Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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0cells of the map it votes in
30citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 35 citations in OpenAlex.
- Mitochondrial heterogeneity across cardiac cell types in heart failure with preserved ejection fraction.Redox biology · 2026Review
- Crosstalk between Ryanodine Receptor 2 Dysfunction and FK506-Binding Proteins in Pulmonary Hypertension.Cardiovascular drugs and therapy · 2026Review
- Crosstalk between Ryanodine Receptor 2 Dysfunction and FK506-Binding Proteins in Pulmonary Hypertension.Cardiovascular drugs and therapy · 2026Review
- Type-1 Ryanodine Receptor Plays an Important Role in Cardiac Hypertrophy and Heart Failure by Increasing Type-2 Ryanodine Receptor-Mediated Calcium Release.International journal of molecular sciences · 2026Article
- FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review).International journal of molecular medicine · 2026Review
- NF-κB signaling as a critical inflammatory node in pulmonary arterial hypertension: from vascular remodeling to right heart failure.Frontiers in immunology · 2026Review
- NF-κB and pulmonary hypertension: Advances in mechanistic research and therapeutic applications.American heart journal plus : cardiology research and practice · 2025Review
- Proteome-wide Mendelian randomization and colocalization analysis uncovers druggable targets for lung cancer across multiple phenotypes and complications.Discover oncology · 2025Article
- Oxidative Stress and Inflammation in Hypoxemic Respiratory Diseases and Their Comorbidities: Molecular Insights and Diagnostic Advances in Chronic Obstructive Pulmonary Disease and Sleep Apnea.Antioxidants (Basel, Switzerland) · 2025Review
- Ubiquitination-mediated upregulation of glycolytic enzyme MCT4 in promoting astrocyte reactivity during neuroinflammation.Journal of neuroinflammation · 2025Article
- Mfn2 regulates calcium homeostasis and suppresses PASMCs proliferation via interaction with IP3R3 to mitigate pulmonary arterial hypertension.Journal of translational medicine · 2025Article
- [Sphingosine kinase-1 regulates migration and invasion of gastric cancer cellsNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- Article
- CC chemokines Modulate Immune responses in Pulmonary Hypertension.Journal of advanced research · 2024Review
- Urolithin A Protects against Hypoxia-Induced Pulmonary Hypertension by Inhibiting Pulmonary Arterial Smooth Muscle Cell Pyroptosis via AMPK/NF-κB/NLRP3 Signaling.International journal of molecular sciences · 2024Article
- Rieske Iron-Sulfur Protein Mediates Pulmonary Hypertension Following Nicotine/Hypoxia Coexposure.American journal of respiratory cell and molecular biology · 2024Article
- Arrhythmogenic mechanism of a novel ryanodine receptor mutation underlying sudden cardiac death.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.Molecular oncology · 2023Article
- Role of ryanodine receptor 2 and FK506-binding protein 12.6 dissociation in pulmonary hypertension.The Journal of general physiology · 2023Article
- Pulmonary Vascular Remodeling in Pulmonary Hypertension.Journal of personalized medicine · 2023Review
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Lin Mei *Department of Molecular and Cellular Physiology, Albany Medical College, Albany, 12208, NY, USA.
Yun-Min Zheng *Department of Molecular and Cellular Physiology, Albany Medical College, Albany, 12208, NY, USA.
Tengyao SongDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, 12208, NY, USA.
Vishal R YadavDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, 12208, NY, USA.
Leroy C JosephDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, 12208, NY, USA.
Lillian TruongDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, 12208, NY, USA.
Sharath KandhiDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, 12208, NY, USA.ORCID http://orcid.org/0000-0002-4674-0325
Margarida M BarrosoDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, 12208, NY, USA.ORCID http://orcid.org/0000-0002-0407-3181
Hiroshi TakeshimaDepartment of Biological Chemistry, Kyoto University Graduate School of Pharmaceutical Sciences, Kyoto, Japan.
Marc A JudsonDivision of Pulmonary and Critical Care Medicine, Albany Medical College, Albany, 12208, NY, USA.
Yong-Xiao WangDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, 12208, NY, USA. WangY@amc.edu.ORCID http://orcid.org/0000-0002-7483-3844
Albany Medical Center Hospital · USKyoto University · JP
Funding
Mechanisms for hypoxic Ca2+ release in pulmonary artery myocytesR01HL064043 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WANG, YONG-XIAO · 2000 to 2010
$2.7MNovel signaling in chronic hypoxic responses in pulmonary arteriesR01HL122865 · NHLBI · ALBANY MEDICAL COLLEGE · PI WANG, YONG-XIAO · 2015 to 2018
$1.9MSignaling Mechanisms for Hypoxic Pulmonary VasoconstrictionR01HL108232 · NHLBI · ALBANY MEDICAL COLLEGE · PI WANG, YONG-XIAO · 2012 to 2015
$1.5MNEWFOUNDLAND BREEDING COLONYZ01HL003401 · NHLBI · HEART, LUNG, AND BLOOD INSTITUTE · PI PIERCE, J E · 1985 to 1986
–NHLBI NIH HHS R01 HL064043NHLBI NIH HHS R01 HL108232NHLBI NIH HHS R01 HL122865
Abstract
Ca
Indexed as
AnimalsCalcium SignalingCell ProliferationCyclin D1CytosolElectron Transport Complex IIIHumansHypertension, PulmonaryHypoxiaMaleMiceMice, Inbred C57BLMice, KnockoutMitochondriaMyocytes, Smooth MuscleNF-kappa BCyclin D1Electron Transport Complex IIINF-kappa BOxygenReactive Oxygen SpeciesRieske iron-sulfur proteinryanodine receptor 2. mouseRyanodine Receptor Calcium Release ChannelRyR2 protein, humantacrolimus binding protein 1BTacrolimus Binding Proteins
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.