Evidence map›Paper›PMID 32669381›Full record

ArticleJournal of clinical microbiology2020

A Highly Prevalent Polymorphism in the Core Region Impairs Quantification of Hepatitis B Virus (HBV) by the cobas TaqMan HBV Assay.

Laure Boizeau, Annabelle Servant-Delmas, Alexandra Ducancelle, Stéphane Chevaliez, Vincent Thibault, Syria Laperche, Pierre Cappy

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Laure BoizeauNational Institute of Blood Transfusion, Department of Blood-Borne Agents, National Reference Center for Infectious Risks in Transfusion, Paris, France.
Annabelle Servant-DelmasNational Institute of Blood Transfusion, Department of Blood-Borne Agents, National Reference Center for Infectious Risks in Transfusion, Paris, France.
Alexandra DucancelleLaboratory of Virology, Angers University Hospital, Angers, France.
Stéphane ChevaliezDepartment of Virology, Henri Mondor Hospital, National Reference Center for Viral Hepatitis B, C and Delta, INSERM U955, Université Paris-Est, Créteil, France.
Vincent ThibaultCHU Rennes, INSERM, EHESP, Institut de Recherche en Santé, Environnement et Travail (IRSET) - UMR_S 1085, Virology Unit Rennes, Rennes, France.ORCID 0000-0001-6517-2901
Syria LapercheNational Institute of Blood Transfusion, Department of Blood-Borne Agents, National Reference Center for Infectious Risks in Transfusion, Paris, France slaperche@ints.fr pcappy@ints.fr.
Pierre CappyNational Institute of Blood Transfusion, Department of Blood-Borne Agents, National Reference Center for Infectious Risks in Transfusion, Paris, France slaperche@ints.fr pcappy@ints.fr.ORCID 0000-0001-8540-2196
Institut National de la Transfusion Sanguine · FRInserm · FRCentre Hospitalier Universitaire d'Angers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high genetic variability of hepatitis B virus (HBV) can impair DNA quantification. Here, we investigate a major underquantification of HBV by the cobas TaqMan HBV assay (CTM; Roche). In France, between 2005 and 2017, HBV DNA was detected in 3,102 blood donations by use of the CTM (95% limit of detection [LOD

Indexed as

DNA, ViralHepatitis B virusEuropeFranceHumansViral LoadDNA, Viraldiagnosishepatitis B virusplasma viral loadunderquantificationviral surveillance

Identifiers

PMID32669381
PMCPMC7448625
OpenAlexW3041392699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.