Evidence map›Paper›PMID 32669353›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

α-Synuclein Induces Progressive Changes in Brain Microstructure and Sensory-Evoked Brain Function That Precedes Locomotor Decline.

Winston T Chu, Jesse C DeSimone, Cara J Riffe, Han Liu, Paramita Chakrabarty, Benoit I Giasson, Vinata Vedam-Mai, David E Vaillancourt

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Multiple system atrophy related neurogenic bladder: mechanism and treatment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Winston T ChuJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611.ORCID 0000-0001-7818-9139
Jesse C DeSimoneDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida 32611.
Cara J RiffeDepartment of Neuroscience, University of Florida, Gainesville, Florida 32611.
Han LiuJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611.
Paramita ChakrabartyDepartment of Neuroscience, University of Florida, Gainesville, Florida 32611.
Benoit I GiassonDepartment of Neuroscience, University of Florida, Gainesville, Florida 32611.
Vinata Vedam-MaiDepartment of Neurology, University of Florida, Gainesville, Florida 32611.
David E VaillancourtJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611 vcourt@ufl.edu.
University of Florida · US

Funding

Non-Invasive Markers of Neurodegeneration in Movement DisordersR01NS075012 · NINDS · UNIVERSITY OF FLORIDA · PI LI, YUQING, VAILLANCOURT, DAVID E · 2012 to 2022
$4.1M
Mechanisms of Aggregated Alpha-Synuclein Induction and ProgressionR01NS089622 · NINDS · UNIVERSITY OF FLORIDA · PI GIASSON, BENOIT I · 2014 to 2018
$1.6M
Adoptive Cell Therapies and Translational Neuroimaging in SynucleinopathyR56NS112401 · NINDS · UNIVERSITY OF FLORIDA · PI VEDAM-MAI, VINATA · 2019 to 2019
$534k
Upgrade of an 11T/40cm MRI/S SystemS10RR025671 · NCRR · UNIVERSITY OF FLORIDA · PI EDISON, ARTHUR S · 2009 to 2009
$500k
NCRR NIH HHS S10 RR025671NINDS NIH HHS R01 NS075012NINDS NIH HHS R01 NS089622NINDS NIH HHS R56 NS112401
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Evoked Potentials, Somatosensoryalpha-SynucleinAnimalsBehavior, AnimalBrainBrain MappingDiffusion Magnetic Resonance ImagingFemaleHot TemperatureHumansLocomotionMaleMice, TransgenicPhysical StimulationSynucleinopathiesalpha-Synucleindiffusion MRIlongitudinalmouseresting-state fMRIsensory-evoked fMRIα-synuclein

Identifiers

PMID32669353
PMCPMC7486650
OpenAlexW3042697733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.