Evidence map›Paper›PMID 32669111›Full record

ArticleTrials2020

Effects of Supervised Early Resistance Training versus standard care on cognitive recovery following cardiac surgery via median sternotomy (the SEcReT study): protocol for a randomised controlled pilot study.

Jacqueline M S Pengelly, Alistair G Royse, Adam L Bryant, Gavin P Williams, Lynda J Tivendale, Timothy J Dettmann, David J Canty, Colin F Royse, Doa A El-Ansary

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jacqueline M S PengellyDepartment of Nursing and Allied Health, Swinburne University of Technology, Hawthorn, Melbourne, Victoria, Australia. jpengelly@swin.edu.au.ORCID http://orcid.org/0000-0001-8618-1532
Alistair G RoyseDepartment of Surgery, University of Melbourne, Melbourne, Victoria, Australia.
Adam L BryantDepartment of Physiotherapy, University of Melbourne, Parkville, Victoria, Australia.
Gavin P WilliamsDepartment of Physiotherapy, University of Melbourne, Parkville, Victoria, Australia.
Lynda J TivendaleDepartment of Cardiothoracic Surgery, Royal Melbourne Hospital, Parkville, Victoria, Australia.
Timothy J DettmannKieser Australia, South Melbourne, Victoria, Australia.
David J CantyDepartment of Surgery, University of Melbourne, Melbourne, Victoria, Australia.
Colin F RoyseDepartment of Surgery, University of Melbourne, Melbourne, Victoria, Australia.
Doa A El-AnsaryDepartment of Nursing and Allied Health, Swinburne University of Technology, Hawthorn, Melbourne, Victoria, Australia.
The University of Melbourne · AUThe Royal Melbourne Hospital · AUSwinburne University of Technology · AU

Funding

Department of Surgery, University of Melbourne N/A
6 · The paper itself

Abstract

introductionMild cognitive impairment is considered a precursor to dementia and significantly impacts upon quality of life. The prevalence of mild cognitive impairment is higher in the post-surgical cardiac population than in the general population, with older age and comorbidities further increasing the risk of cognitive decline. Exercise improves neurogenesis, synaptic plasticity and inflammatory and neurotrophic factor pathways, which may help to augment the effects of cognitive decline. However, the effects of resistance training on cognitive, functional and overall patient-reported recovery have not been investigated in the surgical cardiac population. This study aims to determine the effect of early moderate-intensity resistance training, compared to standard care, on cognitive recovery following cardiac surgery via a median sternotomy. The safety, feasibility and effect on functional recovery will also be examined.

methodsThis study will be a prospective, pragmatic, pilot randomised controlled trial comparing a standard care group (low-intensity aerobic exercise) and a moderate-intensity resistance training group. Participants aged 18 years and older with coronary artery and/or valve disease requiring surgical intervention will be recruited pre-operatively and randomised 1:1 to either the resistance training or standard care group post-operatively. The primary outcome, cognitive function, will be assessed using the Alzheimer's Disease Assessment Scale and cognitive subscale. Secondary measures include safety, feasibility, muscular strength, physical function, multiple-domain quality of recovery, dynamic balance and patient satisfaction. Assessments will be conducted at baseline (pre-operatively) and post-operatively at 2 weeks, 8 weeks, 14 weeks and 6 months. DISCUSSION: The results of this pilot study will be used to determine the feasibility of a future large-scale randomised controlled trial that promotes the integration of early resistance training into existing aerobic-based cardiac rehabilitation programs in Australia.

trial registrationAustralian New Zealand Clinical Trials Registry (ANZCTR) ACTRN12617001430325p . Registered on 9 October 2017. Universal Trial Number (UTN): U1111-1203-2131.

Indexed as

CognitionExercise TherapyResistance TrainingAustraliaCardiac Surgical ProceduresHumansPilot ProjectsPragmatic Clinical Trials as TopicProspective StudiesQuality of LifeRandomized Controlled Trials as TopicSternotomyTreatment OutcomeCardiac surgeryCognitionExerciseMedian sternotomyRecoveryRehabilitationResistance training

Identifiers

PMID32669111
PMCPMC7362413
OpenAlexW3042808286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.