SynthesisBMC cardiovascular disorders2020
The predictive value of lymphocyte-to-monocyte ratio in the prognosis of acute coronary syndrome patients: a systematic review and meta-analysis.
Synthesis in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Naples Prognostic Score and Clinical Outcomes After PCI for Acute Coronary Syndrome: A Systematic Review and Meta-Analysis.Clinical cardiology · 2026Pooled it
- Association of Hematological Inflammatory Markers with T-MACS-Based Risk Stratification in Patients with Non-ST-Elevation Acute Coronary Syndrome.Journal of clinical medicine · 2026Article
- Inflammation-Based Hematologic Indices as Prognostic Markers in Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension: A Hypothesis-Generating Registry Study.International journal of molecular sciences · 2025Article
- Prognostic impact of Naples prognostic score on long-term mortality in non-ST-elevation myocardial infarction.Biomarkers in medicine · 2025Article
- Coronary Artery Spasm: From Physiopathology to Diagnosis.Life (Basel, Switzerland) · 2025Review
- Structural and functional brain correlates of the neutrophil- and monocyte-to-lymphocyte ratio in neuropsychiatric disorders.Brain, behavior, & immunity - health · 2025Article
- Prognostic Value of Systemic Inflammation Scores in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: A Prospective Cohort Study.Journal of inflammation research · 2025Article
- Prognostic value of lymphocyte-to-monocyte ratio in acute ischemic stroke: a systematic review and meta-analysis.Frontiers in neurology · 2025Review
- Precision phenotyping from routine laboratory parameters for out of hospital survival prediction in an all comers prospective PCI registry.Scientific reports · 2024Article
- Hematological parameters and early-onset coronary artery disease: a retrospective case-control study based on 3366 participants.Therapeutic advances in chronic disease · 2023Article
- The Significance of Simple Inflammatory Markers in Off Pump Surgery-Review.Reviews in cardiovascular medicine · 2022Review
- Predicting Major Adverse Cardiovascular Events in Acute Coronary Syndrome: A Scoping Review of Machine Learning Approaches.Applied clinical informatics · 2022Article
- Lymphocyte-to-Monocyte Ratio Is Independently Associated with Progressive Infarction in Patients with Acute Ischemic Stroke.BioMed research international · 2022Article
- NLRP3 Inflammasome May Be a Biomarker for Risk Stratification in Patients with Acute Coronary Syndrome.Journal of inflammation research · 2022Article
- Development and Validation of a Risk Nomogram Model for Predicting Recurrence in Patients with Atrial Fibrillation After Radiofrequency Catheter Ablation.Clinical interventions in aging · 2022Observational
- Monocyte-to-Lymphocyte Ratio as a Predictor of Worse Long-Term Survival after Off-Pump Surgical Revascularization-Initial Report.Medicina (Kaunas, Lithuania) · 2021Article
- Association of the lymphocyte-to-monocyte ratio, mean diameter of coronary arteries, and uric acid level with coronary slow flow in isolated coronary artery ectasia.BMC cardiovascular disorders · 2021Article
- Diagnostic blood RNA profiles for human acute spinal cord injury.The Journal of experimental medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundThe association between the lymphocyte-to-monocyte ratio (LMR) and prognosis in the patients with acute coronary syndrome (ACS) is not fully understood. We performed this systematic review and meta-analysis to evaluate the correlation between LMR and mortality or major adverse cardiac events (MACE) in patients with ACS.
methodsA systematic search was performed in PubMed, MEDLINE, EMBASE, the Cochrane Library, Scopus, and Web of science. The association between LMR and mortality/MACE was analyzed in patients with ACS. The search was updated to April 15, 2020.
resultsA total of 5 studies comprising 4343 patients were included in this meta-analysis. The results showed that lower LMR predicted higher short-term mortality/MACE (hazard ratio [HR] = 3.44, 95% confidence interval [CI]: 1.46-8.14, P < 0.05) and long-term mortality/MACE (HR = 1.70, 95% CI: 1.36-2.13, P < 0.05). In the subgroup analysis, there was still statistical significance of long-term mortality/MACE in all subgroups.
conclusionsThis study suggested that lower LMR value might be associated with higher short-term and long-term mortality/MACE in ACS patients. Especially for younger ACS patients, low LMR was more closely associated with poor prognosis.
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