Evidence map›Paper›PMID 32668631›Full record

ArticleMolecules (Basel, Switzerland)2020

4-Arylthieno[2,3-

Sandra I Schweda, Arne Alder, Tim Gilberger, Conrad Kunick

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. β-Ketoamides in Thieno[2,3-Molecules (Basel, Switzerland) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sandra I SchwedaInstitut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, 38106 Braunschweig, Germany.ORCID 0000-0001-7141-812X
Arne AlderCentre for Structural Systems Biology, 22607 Hamburg, Germany.
Tim GilbergerCentre for Structural Systems Biology, 22607 Hamburg, Germany.ORCID 0000-0002-7965-8272
Conrad KunickInstitut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, 38106 Braunschweig, Germany.ORCID 0000-0001-7041-5322

Funding

Evangelisches Studienwerk Villigst NoneJuergen Manchot-Stiftung NoneOpen Access Publication Funds of the Technische Universität Braunschweig None
6 · The paper itself

Abstract

Malaria causes hundreds of thousands of deaths every year, making it one of the most dangerous infectious diseases worldwide. Because the pathogens have developed resistance against most of the established anti-malarial drugs, new antiplasmodial agents are urgently needed. In analogy to similar antiplasmodial ketones, 4-arylthieno[2,3-

Indexed as

AmidesAntimalarialsDrug DiscoveryHEK293 CellsHumansPlasmodium falciparumStructure-Activity RelationshipThienopyridinesAmidesAntimalarialsThienopyridinesanti-malarial drugsantiplasmodialmalariaPfGSK-3Plasmodium falciparumthieno[2,3-b]pyridineThorpe-Ziegler reaction

Identifiers

PMID32668631
PMCPMC7397174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.