Evidence map›Paper›PMID 32668607›Full record

ReviewInternational journal of environmental research and public health2020

Insufficient Sun Exposure Has Become a Real Public Health Problem.

Lars Alfredsson, Bruce K Armstrong, D Allan Butterfield, Rajiv Chowdhury, Frank R de Gruijl, Martin Feelisch, Cedric F Garland, Prue H Hart, David G Hoel, Ramune Jacobsen and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
8.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 148 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Sleep Duration and Sun Exposure in Portuguese Children: Associations With Obesity Indicators.American journal of human biology : the official journal of the Human Biology Council · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Beneficial health effects of ultraviolet radiation: expert review and conference report.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Self-Reported Outdoor Light Exposure Time and Incident Heart Failure.Journal of the American Heart Association · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 14 institutions in 6 countries.

Lars AlfredssonInstitute of Environmental Medicine, Karolinska Institute, 171 77 Stockholm, Sweden.
Bruce K ArmstrongSchool of Population and Global Health, The University of Western Australia, Perth 6009, Australia.
D Allan ButterfieldDepartment of Chemistry and Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40506, USA.ORCID 0000-0003-3254-5286
Rajiv ChowdhuryCardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.
Frank R de GruijlDepartment of Dermatology, Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands.
Martin FeelischClinical & Experimental Sciences, University of Southampton Medical School and University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
Cedric F GarlandDivision of Epidemiology, Department of Family Medicine and Public Health, University of California San Diego School of Medicine, La Jolla, CA 92093, USA.
Prue H HartTelethon Kids Institute, University of Western Australia, Perth 6872, Australia.ORCID 0000-0001-7207-6467
David G HoelDepartment of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-1178-1610
Ramune JacobsenDepartment of Pharmacy, University of Copenhagen, DK-2100 Copenhagen, Denmark.ORCID 0000-0002-8142-9807
Pelle G LindqvistDepartment of Clinical Science and Education, Karolinska Institute, 171 77 Stockholm, Sweden.ORCID 0000-0002-1652-8235
David J LlewellynCollege of Medicine and Health, University of Exeter Medical School, Exeter EX1 2LU, UK.
Henning TiemeierDepartment of Social and Behavioral Science, Harvard T.H. Chan School of Public Health, Harvard University, Cambridge, MA 02115, USA.
Richard B WellerCentre for Inflammation Research, University of Edinburgh, Edinburgh EH16 4SB, UK.ORCID 0000-0003-2550-9586
Antony R YoungSt John's Institute of Dermatology, King's College London, London SE1 9RT, UK.
Karolinska Institutet · SECentre for Inflammation Research · GBHarvard University · USKing's College London · GBLeiden University · NLMedical University of South Carolina · USThe Kids Research Institute Australia · AUThe University of Western Australia · AUUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of California San Diego · USUniversity of Cambridge · GBUniversity of Copenhagen · DKUniversity of Exeter · GBUniversity of Kentucky · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article aims to alert the medical community and public health authorities to accumulating evidence on health benefits from sun exposure, which suggests that insufficient sun exposure is a significant public health problem. Studies in the past decade indicate that insufficient sun exposure may be responsible for 340,000 deaths in the United States and 480,000 deaths in Europe per year, and an increased incidence of breast cancer, colorectal cancer, hypertension, cardiovascular disease, metabolic syndrome, multiple sclerosis, Alzheimer's disease, autism, asthma, type 1 diabetes and myopia. Vitamin D has long been considered the principal mediator of beneficial effects of sun exposure. However, oral vitamin D supplementation has not been convincingly shown to prevent the above conditions; thus, serum 25(OH)D as an indicator of vitamin D status may be a proxy for and not a mediator of beneficial effects of sun exposure. New candidate mechanisms include the release of nitric oxide from the skin and direct effects of ultraviolet radiation (UVR) on peripheral blood cells. Collectively, this evidence indicates it would be wise for people living outside the tropics to ensure they expose their skin sufficiently to the sun. To minimize the harms of excessive sun exposure, great care must be taken to avoid sunburn, and sun exposure during high ambient UVR seasons should be obtained incrementally at not more than 5-30 min a day (depending on skin type and UV index), in season-appropriate clothing and with eyes closed or protected by sunglasses that filter UVR.

Indexed as

Public HealthSunlightUltraviolet RaysEuropeHumansSunburnVitamin DVitamin D DeficiencyVitamin Ddisease preventionnitric oxidesun exposureUV radiationvitamin D

Identifiers

PMID32668607
PMCPMC7400257
OpenAlexW3040994624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.