Evidence map›Paper›PMID 32668589›Full record

ArticleMolecules (Basel, Switzerland)2020

Versatile Polypeptide-Functionalized Plasmonic Paper as Synergistic Biocompatible and Antimicrobial Nanoplatform.

Leopold Tie, Mina Răileanu, Mihaela Bacalum, Irina Codita, Ștefania Mădălina Negrea, Costin Ștefan Caracoti, Elena-Carmina Drăgulescu, Andreea Campu, Simion Astilean, Monica Focsan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Leopold TieNanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babes-Bolyai University, Treboniu Laurean No.42, 400271 Cluj-Napoca, Romania.
Mina RăileanuDepartment of Life and Environmental Physics, Horia Hulubei National Institute of Physics and Nuclear Engineering, 30 Reactorului Street, 077125 Magurele, Romania.
Mihaela BacalumDepartment of Life and Environmental Physics, Horia Hulubei National Institute of Physics and Nuclear Engineering, 30 Reactorului Street, 077125 Magurele, Romania.ORCID 0000-0002-7309-6002
Irina CoditaCantacuzino National Medical-Military Institute for Research-Development, Splaiul Independenței 103, 050096 Bucharest, Romania.
Ștefania Mădălina NegreaCantacuzino National Medical-Military Institute for Research-Development, Splaiul Independenței 103, 050096 Bucharest, Romania.
Costin Ștefan CaracotiCantacuzino National Medical-Military Institute for Research-Development, Splaiul Independenței 103, 050096 Bucharest, Romania.
Elena-Carmina DrăgulescuCantacuzino National Medical-Military Institute for Research-Development, Splaiul Independenței 103, 050096 Bucharest, Romania.
Andreea CampuNanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babes-Bolyai University, Treboniu Laurean No.42, 400271 Cluj-Napoca, Romania.
Simion AstileanNanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babes-Bolyai University, Treboniu Laurean No.42, 400271 Cluj-Napoca, Romania.ORCID 0000-0002-9975-5651
Monica FocsanNanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babes-Bolyai University, Treboniu Laurean No.42, 400271 Cluj-Napoca, Romania.ORCID 0000-0001-6735-5146
Babeș-Bolyai University · ROHoria Hulubei National Institute for R and D in Physics and Nuclear Engineering · ROUniversity of Bucharest · RO

Funding

Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii PN-III-P1-1.2-PCCDI-2017-0010 / 74PCCDI ⁄ 2018, within PNCDI III.
6 · The paper itself

Abstract

Nowadays, thanks to nanotechnological progress, which itself guides us more and more closely toward not only the efficient design of innovative nanomaterials or nanostructures, but to the improvement of their functionality, we benefit from an important asset in the battle against pathogenic illnesses. Herein, we report a versatile biocompatible plasmonic nanoplatform based on a Whatman paper incorporating positively-charged gold nanospherical particles via the immersion approach. The morphological characterization of the as-engineered-plasmonic paper was examined by SEM (scanning electron microscopy) and HRTEM (high-resolution transmission electron microscopy) investigations, while its surface chemical modification with a synthetic polypeptide, specifically RRWHRWWRR-NH2 (P2), was proved by monitoring the plasmonic response of loaded gold nanospheres and the emission signal of P2 via fluorescence spectroscopy. The as-functionalized plasmonic paper is non-cytotoxic towards BJ fibroblast human cells at bactericidal concentrations. Finally, the antimicrobial activity of the P2-functionalized plasmonic paper on both planktonic bacteria and biofilms was tested against two reference strains: Gram-positive Bacteria, i.e.,

Indexed as

Anti-Bacterial AgentsBiocompatible MaterialsBiofilmsCell LineEscherichia coliGoldHumansMetal NanoparticlesPaperPeptidesStaphylococcus aureusAnti-Bacterial AgentsBiocompatible MaterialsGoldPeptidesantimicrobial activityantimicrobial peptidesbiocompatibilityEscherichia coligold nanospherespaper platformStaphylococcus aureus

Identifiers

PMID32668589
PMCPMC7397136
OpenAlexW3040870285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.