ArticleSports (Basel, Switzerland)2020
Effect of
Article in Sports (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- ACTN3 c.1729C>T Polymorphism Might Not Be a Standalone Factor in Non-contact Musculoskeletal Injury: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- A Systematic Review and Meta-analysis of the Association Between ACTN3 R577X Genotypes and Performance in Endurance Versus Power Athletes and Non-athletes.Sports medicine - open · 2024Pooled it
- Association between ACTN3 R577X genotype and risk of non-contact injury in trained athletes: A systematic review.Journal of sport and health science · 2023Pooled it
- Genetics and athletic performance: a systematic SWOT analysis of non-systematic reviews.Frontiers in genetics · 2023Pooled it
- The X genotype of the ACTN3 sports gene is associated with the endurance of the sportsperson from the South Indian population: a short study.European journal of applied physiology · 2026Article
- Higher Incidence and Longer Recovery Time from Non-Contact Muscle Injuries in ACTN3 XX Genotype Players from a Soccer Academy: A Three-Season Longitudinal Study.Sports medicine - open · 2026Article
- Kinetics of Serum Myoglobin and Creatine Kinase Related to Exercise-Induced Muscle Damage andJournal of functional morphology and kinesiology · 2025Article
- Structural and functional insights into α-actinin isoforms and their implications in cardiovascular disease.The Journal of general physiology · 2025Review
- Impact of ACTN3 R577X Polymorphism on Muscle Damage Susceptibility Following Aerobic or Strength Exercises: A Systematic Review.International journal of preventive medicine · 2025Review
- Article
- The Genetic Basis of Non-Contact Soft Tissue Injuries-Are There Practical Applications of Genetic Knowledge?Cells · 2024Review
- Influence of genetic polymorphism on sports talent performance versus non-athletes: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2024Article
- Article
- Association of theGenes · 2023Article
- Identification of Perception Differences in Personality Factors and Autonomy by Sporting Age Category in Competitive Bodybuilders.International journal of environmental research and public health · 2022Article
- Association of theGenes · 2022Article
- Influence of Alpha-Actinin-3 R577X Polymorphism on Muscle Damage and the Inflammatory Response after an Acute Strength Training Session.BioMed research international · 2022Article
- Whole Genome Interpretation for a Family of Five.Frontiers in genetics · 2021Article
- The role of genetic and epigenetic factors in sports-related muscle, bone, and brain injuries.Science progressReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic factors play a significant role in athletic performance and its related phenotypes such as power, strength and aerobic capacity. In this regard, the lack of a muscle protein due to a genetic polymorphism has been found to affect sport performance in a wide variety of ways. α-actinin-3 is a protein located within the skeletal muscle with a key role in the production of sarcomeric force. A common stop-codon polymorphism (rs1815739; R577X) in the gene that codes for α-actinin-3 (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.