ArticleJournal of clinical medicine2020
Limited Agreement between Classifications of Diabetes and Prediabetes Resulting from the OGTT, Hemoglobin A1c, and Fasting Glucose Tests in 7412 U.S. Adults.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Diagnosing Diabetes in Cohort Studies: The Case for Comprehensive Glycemic Assessment.Geriatrics & gerontology international · 2026Article
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- Glucose Abnormalities Detected by Continuous Glucose Monitoring in Very Old Adults With and Without Diabetes.Diabetes care · 2025Article
- A software tool for applying Bayes' theorem in medical diagnostics.BMC medical informatics and decision making · 2024Article
- Evidence-based screening, clinical care and health education recommendations for Alaska Native peoples with prediabetes living in southcentral Alaska: findings from the Alaska EARTH follow-up study.International journal of circumpolar health · 2024Article
- Continuous Glucose Monitoring for Prediabetes: What Are the Best Metrics?Journal of diabetes science and technology · 2024Review
- A Software Tool for Estimating Uncertainty of Bayesian Posterior Probability for Disease.Diagnostics (Basel, Switzerland) · 2024Article
- A Bayesian Inference Based Computational Tool for Parametric and Nonparametric Medical Diagnosis.Diagnostics (Basel, Switzerland) · 2023Article
- Prevalence and characteristics of metabolic syndrome and its components among adults living with and without HIV in Nigeria: a single-center study.BMC endocrine disorders · 2023Article
- Association between the insulin resistance marker TyG index and subsequent adverse long-term cardiovascular events in young and middle-aged US adults based on obesity status.Lipids in health and disease · 2023Article
- The Importance of Prediabetes Screening in the Prevention of Cardiovascular Disease.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2023Article
- Prevalence of haemoglobin A1c based dysglycaemia among adult community dwellers in selected states in Nigeria: a descriptive cross-sectional study.Frontiers in endocrinology · 2023Article
- Haemoglobin A1c-based screening for prediabetes and diabetes mellitus: a multi-center study in Croatian adult population.Biochemia medica · 2022Article
- Serum Glucose Measurement after Five to Six Hours is Comparable to Eight Hours Fasting in Ramadan.Sultan Qaboos University medical journal · 2022Observational
- Serum IRAP, a Novel Direct Biomarker of Prediabetes and Type 2 Diabetes?Frontiers in molecular biosciences · 2020Article
- The Triglyceride-Glucose Index, an Insulin Resistance Marker, Was Non-linear Associated With All-Cause and Cardiovascular Mortality in the General Population.Frontiers in cardiovascular medicine · 2020Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This investigation was designed to determine the degree of concordance resulting from tests of fasting plasma glucose (FPG) and hemoglobin A1c (A1c) compared to the oral glucose tolerance test (OGTT) for detecting prediabetes and diabetes in undiagnosed adults. Another objective was to measure concordance within subsamples of women and men, and within three age groups. Lastly, the value of combining the FPG and A1c for detecting diabetes was compared to the OGTT. A total of 7412 randomly selected adults from the National Health and Nutrition Examination Survey (NHANES) were included. With outcomes classified as normal, prediabetes, or diabetes, according to standard guidelines, overall test agreements were low. With an OGTT diagnosis of diabetes, concordance was only 34% for the A1c assessment and 44% for the FPG assay. Delimited to older adults, agreement between the OGTT and A1c was only 25%, and between the OGTT and FPG, concordance was only 33.5%. Given the large percentage of discordant results associated with the FPG and A1c, clinicians should be cautious about employing these tests as lone assessments. Using both the FPG and A1c helped with accurately diagnosing diabetes and normal glycemia, but not prediabetes. The OGTT is a good choice to reduce misdiagnosis.
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